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MULTISPECIES: two-component system response regulator PmrA


LOCUS       WP_002895659             223 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002895659
VERSION     WP_002895659.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 223)
  AUTHORS   Luo,S.C., Lou,Y.C., Rajasekaran,M., Chang,Y.W., Hsiao,C.D. and
            Chen,C.
  TITLE     Structural basis of a physical blockage mechanism for the
            interaction of response regulator PmrA with connector protein PmrD
            from Klebsiella pneumoniae
  JOURNAL   J. Biol. Chem. 288 (35), 25551-25561 (2013)
   PUBMED   23861396
REFERENCE   2  (residues 1 to 223)
  AUTHORS   Ogasawara,H., Shinohara,S., Yamamoto,K. and Ishihama,A.
  TITLE     Novel regulation targets of the metal-response BasS-BasR
            two-component system of Escherichia coli
  JOURNAL   Microbiology (Reading, Engl.) 158 (Pt 6), 1482-1492 (2012)
   PUBMED   22442305
REFERENCE   3  (residues 1 to 223)
  AUTHORS   Gunn,J.S.
  TITLE     The Salmonella PmrAB regulon: lipopolysaccharide modifications,
            antimicrobial peptide resistance and more
  JOURNAL   Trends Microbiol. 16 (6), 284-290 (2008)
   PUBMED   18467098
REFERENCE   4  (residues 1 to 223)
  AUTHORS   Gunn,J.S., Lim,K.B., Krueger,J., Kim,K., Guo,L., Hackett,M. and
            Miller,S.I.
  TITLE     PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A
            modification and polymyxin resistance
  JOURNAL   Mol. Microbiol. 27 (6), 1171-1182 (1998)
   PUBMED   9570402
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007928.2
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10643
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..223
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..223
                     /gene="pmrA"
     Protein         1..223
                     /product="two-component system response regulator PmrA"
                     /calculated_mol_wt=25061
     Region          1..222
                     /region_name="PRK10643"
                     /note="two-component system response regulator PmrA"
                     /db_xref="CDD:182612"
ORIGIN      
        1 mkilviedda lllqglilam qsegyvcdgv staheaalsl asnhyslivl dlglpdedgl
       61 hflsrmrrek mtqpvlilta rdtledrisg ldtgaddylv kpfaleelna rirallrrhn
      121 nqgdneisvg nlrlnvtrrl vwlgetaldl tpkeyallsr lmmkagspvh reilyndiys
      181 wdnepatntl evhihnlrek igksrirtvr gfgymlanni dte