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MULTISPECIES: cell envelope integrity protein TolA [Klebsiella].


LOCUS       WP_002895064             440 aa            linear   BCT 17-OCT-2022
ACCESSION   WP_002895064
VERSION     WP_002895064.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 440)
  AUTHORS   Vines,E.D., Marolda,C.L., Balachandran,A. and Valvano,M.A.
  TITLE     Defective O-antigen polymerization in tolA and pal mutants of
            Escherichia coli in response to extracytoplasmic stress
  JOURNAL   J Bacteriol 187 (10), 3359-3368 (2005)
   PUBMED   15866920
REFERENCE   2  (residues 1 to 440)
  AUTHORS   Karlsson,F., Borrebaeck,C.A., Nilsson,N. and Malmborg-Hager,A.C.
  TITLE     The mechanism of bacterial infection by filamentous phages involves
            molecular interactions between TolA and phage protein 3 domains
  JOURNAL   J Bacteriol 185 (8), 2628-2634 (2003)
   PUBMED   12670988
REFERENCE   3  (residues 1 to 440)
  AUTHORS   Walburger,A., Lazdunski,C. and Corda,Y.
  TITLE     The Tol/Pal system function requires an interaction between the
            C-terminal domain of TolA and the N-terminal domain of TolB
  JOURNAL   Mol Microbiol 44 (3), 695-708 (2002)
   PUBMED   11994151
REFERENCE   4  (residues 1 to 440)
  AUTHORS   Journet,L., Bouveret,E., Rigal,A., Lloubes,R., Lazdunski,C. and
            Benedetti,H.
  TITLE     Import of colicins across the outer membrane of Escherichia coli
            involves multiple protein interactions in the periplasm
  JOURNAL   Mol Microbiol 42 (2), 331-344 (2001)
   PUBMED   11703658
REFERENCE   5  (residues 1 to 440)
  AUTHORS   Germon,P., Ray,M.C., Vianney,A. and Lazzaroni,J.C.
  TITLE     Energy-dependent conformational change in the TolA protein of
            Escherichia coli involves its N-terminal domain, TolQ, and TolR
  JOURNAL   J Bacteriol 183 (14), 4110-4114 (2001)
   PUBMED   11418549
REFERENCE   6  (residues 1 to 440)
  AUTHORS   Lubkowski,J., Hennecke,F., Pluckthun,A. and Wlodawer,A.
  TITLE     Filamentous phage infection: crystal structure of g3p in complex
            with its coreceptor, the C-terminal domain of TolA
  JOURNAL   Structure 7 (6), 711-722 (1999)
   PUBMED   10404600
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007065.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09510
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..440
                     /gene="tolA"
     Protein         1..440
                     /product="cell envelope integrity protein TolA"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0019534 - toxin transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /calculated_mol_wt=44573
     Region          1..440
                     /region_name="tolA"
                     /note="cell envelope integrity inner membrane protein
                     TolA; Provisional; PRK09510"
                     /db_xref="CDD:236545"
ORIGIN      
        1 mskateqndk lkraiiisva lhiilialli wssfdehlda saggggssid avmvdpgavv
       61 nnynrqqqqq asarraaeqr ekqaqqqaee lrekqaaeqe rlkqleqerl qaqeaakeak
      121 eqqkqaeeaa akaaaaakak adaqakeaqe aaakaaaeak akadaqakaa eqaaakaaad
      181 akkqaeaaaa kaaaeakkqa eaeaakaaae aqkkaeaaaa kkaqqeaekk aqqeaakqaa
      241 aekaaaekaa ekaaaqkaaa ekaaaekaaa aekaaaakaa aaekaaadka akaaaakaaa
      301 akkaaaakea dgvdnllgdl ssgknapktg ggakgnnasa agsgntknsa sgadinnyag
      361 qiksaieskf ydassyagkt ctlriklapd glllniqseg gdpalcqaal aaarqakfpk
      421 ppsqavyevf knapldfkpq