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MULTISPECIES: 5-oxoprolinase subunit PxpA [Klebsiella].


LOCUS       WP_002894926             247 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002894926
VERSION     WP_002894926.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 247)
  AUTHORS   Niehaus,T.D., Elbadawi-Sidhu,M., de Crecy-Lagard,V., Fiehn,O. and
            Hanson,A.D.
  TITLE     Discovery of a widespread prokaryotic 5-oxoprolinase that was
            hiding in plain sight
  JOURNAL   J. Biol. Chem. 292 (39), 16360-16367 (2017)
   PUBMED   28830929
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003812.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05406
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..247
                     /gene="pxpA"
     Protein         1..247
                     /product="5-oxoprolinase subunit PxpA"
                     /EC_number="3.5.2.9"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=26274
     Region          1..240
                     /region_name="PRK05406"
                     /note="5-oxoprolinase subunit PxpA"
                     /db_xref="CDD:235446"
     Site            order(8,57,68,104,106..107,111,160,163,171,174,218)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:212111"
ORIGIN      
        1 mkidlnadlg egcasdsall qlvssaniac gfhagdavlm qqcvrealkn gvaigahpsf
       61 pdrenfgrta mqlppetvya qvlyqigala aivhaqggel rhvkphgmly nqaakeppla
      121 daiaravrda dadlvlvgla gseliragqh yqlttrqevf adrgyladgs lvprsqpgal
      181 ieseeqalaq tlemvqhnrv rslsgewahv kaetvclhgd gahaldfarr lraafagrni
      241 dvsadle