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MULTISPECIES: 5-oxoprolinase subunit PxpB [Klebsiella].


LOCUS       WP_002894921             218 aa            linear   BCT 06-MAY-2024
ACCESSION   WP_002894921
VERSION     WP_002894921.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 218)
  AUTHORS   Niehaus,T.D., Elbadawi-Sidhu,M., de Crecy-Lagard,V., Fiehn,O. and
            Hanson,A.D.
  TITLE     Discovery of a widespread prokaryotic 5-oxoprolinase that was
            hiding in plain sight
  JOURNAL   J Biol Chem 292 (39), 16360-16367 (2017)
   PUBMED   28830929
REFERENCE   2  (residues 1 to 218)
  AUTHORS   Jacques,D.A., Langley,D.B., Kuramitsu,S., Yokoyama,S., Trewhella,J.
            and Guss,J.M.
  TITLE     The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA
            homologue incorrectly annotated as an allophanate hydrolase
  JOURNAL   Acta Crystallogr D Biol Crystallogr 67 (Pt 2), 105-111 (2011)
   PUBMED   21245531
REFERENCE   3  (residues 1 to 218)
  AUTHORS   Brown,G., Singer,A., Proudfoot,M., Skarina,T., Kim,Y., Chang,C.,
            Dementieva,I., Kuznetsova,E., Gonzalez,C.F., Joachimiak,A.,
            Savchenko,A. and Yakunin,A.F.
  TITLE     Functional and structural characterization of four glutaminases
            from Escherichia coli and Bacillus subtilis
  JOURNAL   Biochemistry 47 (21), 5724-5735 (2008)
   PUBMED   18459799
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00370.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..218
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..218
                     /gene="pxpB"
     Protein         1..218
                     /product="5-oxoprolinase subunit PxpB"
                     /EC_number="3.5.2.9"
                     /GO_function="GO:0017168 - 5-oxoprolinase
                     (ATP-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=24317
     Region          9..211
                     /region_name="CT_C_D"
                     /note="Carboxyltransferase domain, subdomain C and D;
                     cl19310"
                     /db_xref="CDD:473162"
ORIGIN      
        1 mqrarcyllg etavvlelep pvtlesqkri wgltqrltdr eevvevipgm nnitvvlrrp
       61 qemaweaidk lqrwweesda lepeyreisi pviyggeagp dlgdvarhsg lsekqvvelh
      121 ssveymvwfl gfqpgfpyfg glpeqlampr raeprvlvpa gsvgiggsqt giyplatpgg
      181 wqllgrtpla lfdpkreepv llrsgdrvrf vpqkegvc