MULTISPECIES: DNA-binding transcriptional regulator NagC

LOCUS       WP_002894742             406 aa            linear   BCT 13-JAN-2025
            [Klebsiella].
ACCESSION   WP_002894742
VERSION     WP_002894742.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Pennetier,C., Dominguez-Ramirez,L. and Plumbridge,J.
  TITLE     Different regions of Mlc and NagC, homologous transcriptional
            repressors controlling expression of the glucose and
            N-acetylglucosamine phosphotransferase systems in Escherichia coli,
            are required for inducer signal recognition
  JOURNAL   Mol Microbiol 67 (2), 364-377 (2008)
   PUBMED   18067539
REFERENCE   2  (residues 1 to 406)
  AUTHORS   Plumbridge,J.
  TITLE     DNA binding sites for the Mlc and NagC proteins: regulation of
            nagE, encoding the N-acetylglucosamine-specific transporter in
            Escherichia coli
  JOURNAL   Nucleic Acids Res 29 (2), 506-514 (2001)
   PUBMED   11139621
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047937.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..406
                     /gene="nagC"
                     /gene_synonym="nagR"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
     Protein         1..406
                     /product="DNA-binding transcriptional regulator NagC"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=44220
     Region          25..77
                     /region_name="HTH_ARSR"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; cl46857"
                     /db_xref="CDD:481197"
     Region          86..400
                     /region_name="ASKHA_ATPase_ROK_NagC"
                     /note="ATPase-like domain of N-acetylglucosamine repressor
                     (NagC) and similar proteins; cd24075"
                     /db_xref="CDD:466925"
ORIGIN      
        1 mtaggqaqig nvdlvkqlns aavyrlidqh gpisriqiae qsqlapasvt kitrqlierg
       61 likevdqqas tggrraisii aetrnfnaig vrlgrydatl tlydlssktl eeehfplper
      121 tqetlehall niiatfienc qrkireliai svilpglvdp esgvirymph iavenwglvg
      181 alekrfnvtc fvghdirsla laehyfgasq dcedsilvrv hrgtgagiis ngrifigrng
      241 nvgeighiqv dplgerchcg nfgcletvaa naaieqrvrh lleqgyqsrl tpddctikti
      301 ckaankgdal acevieyvgr hlgktiaiai nlfnpqkivv ageiveaekv llpaiegcin
      361 aqalkafrkn lpvvrstldh rsaigafalv kramlngtll qrlles