MULTISPECIES: ShlB/FhaC/HecB family hemolysin secretion/activation

LOCUS       WP_002894704             556 aa            linear   BCT 31-DEC-2024
            protein [Klebsiella].
ACCESSION   WP_002894704
VERSION     WP_002894704.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 556)
  AUTHORS   Aoki,S.K., Diner,E.J., de Roodenbeke,C.T., Burgess,B.R.,
            Poole,S.J., Braaten,B.A., Jones,A.M., Webb,J.S., Hayes,C.S.,
            Cotter,P.A. and Low,D.A.
  TITLE     A widespread family of polymorphic contact-dependent toxin delivery
            systems in bacteria
  JOURNAL   Nature 468 (7322), 439-442 (2010)
   PUBMED   21085179
REFERENCE   2  (residues 1 to 556)
  AUTHORS   Zeth,K.
  TITLE     Structure and evolution of mitochondrial outer membrane proteins of
            beta-barrel topology
  JOURNAL   Biochim Biophys Acta 1797 (6-7), 1292-1299 (2010)
   PUBMED   20450883
REFERENCE   3  (residues 1 to 556)
  AUTHORS   Hertle,R.
  TITLE     The family of Serratia type pore forming toxins
  JOURNAL   Curr Protein Pept Sci 6 (4), 313-325 (2005)
   PUBMED   16101433
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11458196
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..556
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006811 - monoatomic ion transport
                     [Evidence IEA]"
                     /GO_process="GO:0015031 - protein transport [Evidence
                     IEA]"
                     /calculated_mol_wt=61993
     Region          11..556
                     /region_name="FhaC"
                     /note="Hemolysin activation/secretion protein
                     [Intracellular trafficking, secretion, and vesicular
                     transport]; COG2831"
                     /db_xref="CDD:442079"
ORIGIN      
        1 mlirsrtltg llfitlagts aagaaplass thqteqdkar qealapqqqd fqssqqrvap
       61 qgipfpeeth cklinrvdid sdnqaltrkl laktarqaqg rclgsegirl laytlqneli
      121 aqgyitslid vpsqslehgi lrftlhygkv gaidyadgsd ttrlwnslpt ssgtilrlsd
      181 leqgmanlqr lpgatahmkl lpgqhegesd iqiarslakk wqlgawldda gskasgryqa
      241 ggalylydlt tlndilylsg ggdiefnqhn dgnhngslyy sipfgywtls aygaysqyrq
      301 qfngnwstmd yksknryysa tlsrllshtr qqkttadlri akstshyyfg gsellvmrkq
      361 npsweftlnh qhyfnnkivd asigiqrslp wlsstatpee qaglysplsr ivhgnlqamm
      421 kfdatgdkft waprlsaqfs pdklasdnkf nigsrwsvrg fdgenslsgn qgwywrndfi
      481 wdlatherqf ylgadigrli gadlyqkgkv lsgavsglrg qlwstqydlf istplskpdk
      541 fhsdalnmgf slqwry