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MULTISPECIES: lipoyl synthase [Klebsiella].


LOCUS       WP_002894467             321 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002894467
VERSION     WP_002894467.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 321)
  AUTHORS   Ollagnier-de Choudens,S. and Fontecave,M.
  TITLE     The lipoate synthase from Escherichia coli is an iron-sulfur
            protein
  JOURNAL   FEBS Lett. 453 (1-2), 25-28 (1999)
   PUBMED   10403368
REFERENCE   2  (residues 1 to 321)
  AUTHORS   Sulo,P. and Martin,N.C.
  TITLE     Isolation and characterization of LIP5. A lipoate biosynthetic
            locus of Saccharomyces cerevisiae
  JOURNAL   J. Biol. Chem. 268 (23), 17634-17639 (1993)
   PUBMED   8349643
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00510.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..321
                     /gene="lipA"
     Protein         1..321
                     /product="lipoyl synthase"
                     /EC_number="2.8.1.8"
                     /GO_function="GO:0016992 - lipoate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35960
     Region          22..321
                     /region_name="LipA"
                     /note="Lipoate synthase [Coenzyme transport and
                     metabolism]; COG0320"
                     /db_xref="CDD:440089"
ORIGIN      
        1 mskpivmerg vkyrdadkma lipvknvate reallrkpew mkiklpadss riqgikaamr
       61 knglhsvcee ascpnlaecf nhgtatfmil gaictrrcpf cdvahgrpva pdanepqkla
      121 qtiadmglry vvvtsvdrdd lrdggaqhfa dcisairekn psikietlvp dfrgrmdral
      181 diltvtppdv fnhnlenvpr lyrqvrpgad ynwslkller fkeahpeipt ksglmvglge
      241 tndeiievmr dlrrhgvtml tlgqylqpsr hhlpvqryvs peefeemkae amamgfthaa
      301 cgpfvrssyh adlqakgmev k