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LOCUS WP_002893907 100 aa linear BCT 24-DEC-2024 [Klebsiella]. ACCESSION WP_002893907 VERSION WP_002893907.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 100) AUTHORS Hall,A.M., Gollan,B. and Helaine,S. TITLE Toxin-antitoxin systems: reversible toxicity JOURNAL Curr Opin Microbiol 36, 102-110 (2017) PUBMED 28279904 REFERENCE 2 (residues 1 to 100) AUTHORS Fiebig,A., Castro Rojas,C.M., Siegal-Gaskins,D. and Crosson,S. TITLE Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems JOURNAL Mol Microbiol 77 (1), 236-251 (2010) PUBMED 20487277 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10005193 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..100 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..100 /product="type II toxin-antitoxin system RelE family toxin" /GO_component="GO:0110001 - toxin-antitoxin complex [Evidence IEA]" /GO_function="GO:0004521 - RNA endonuclease activity [Evidence IEA]" /GO_process="GO:0017148 - negative regulation of translation [Evidence IEA]" /calculated_mol_wt=11639 Region 2..80 /region_name="RelE" /note="mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system [Defense mechanisms]; COG2026" /db_xref="CDD:441629" ORIGIN 1 mkivwsktad kqfskidtry ksriksrlek mddkaspisd ikklsspenh yrlrlgdyrv 61 iytfgdppgd tcyvvavkrr ttttylheed teydysvhqg