MULTISPECIES: betaine-aldehyde dehydrogenase [Klebsiella].

LOCUS       WP_002893471             490 aa            linear   BCT 13-MAY-2021
ACCESSION   WP_002893471
VERSION     WP_002893471.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009725.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13252
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..490
                     /gene="betB"
     Protein         1..490
                     /product="betaine-aldehyde dehydrogenase"
                     /EC_number="1.2.1.8"
                     /GO_function="GO:0008802 - betaine-aldehyde dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /calculated_mol_wt=52771
     Region          1..490
                     /region_name="PRK13252"
                     /note="betaine aldehyde dehydrogenase; Provisional"
                     /db_xref="CDD:183918"
     Site            order(64,66,70,73,77,80,114,118,125..129,137,139..141,235,
                     247,269,272,275..276,309,324,422..425,428..429,431,434,
                     436..439,441..442,450,452,456,458,461,463,475..480,
                     482..483)
                     /site_type="other"
                     /note="tetrameric interface [polypeptide binding]"
                     /db_xref="CDD:143409"
     Site            order(149..150,152..153,176,209,227,229..230,233,252..254,
                     286,387,389,453)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:143409"
     Site            order(153,252,283,286)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
ORIGIN      
        1 msrmaeqqly inggytsats grtfetinpa tgevlatvqa agredvdrav esaqrgqkiw
       61 aamtamersr ilrravdllr qrndelarle tldtgkplse taavdivtga dvleyyagli
      121 palegsqipl rdssfvytrr eplgvvagig awnypiqial wksapalaag namifkpsev
      181 tpltalklae iyseaglpdg vfnvlpgiga etgqyltehp diakisftgg vasgkkvman
      241 saasslkevt melggkspli iaddadldla adiammanfy ssgqvctngt rvfvpakqka
      301 efehkilerv arirpgdlfa ddtnfgplvs fphrdnvlry iesgkregar llcggealkg
      361 dgfdngawva ptvftdcsde mtivreeifg pvmsilsyad eaevirrana teyglaagvv
      421 tpnlnrahri ihqleagicw inswgespae mpvggykhsg igrengvmtl qsytqvksiq
      481 vemgkfqsif