MULTISPECIES: SIS domain-containing protein [Klebsiella].

LOCUS       WP_002893005             353 aa            linear   BCT 26-FEB-2025
ACCESSION   WP_002893005
VERSION     WP_002893005.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 353)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
REFERENCE   2  (residues 1 to 353)
  AUTHORS   Teplyakov,A., Obmolova,G., Badet-Denisot,M.A., Badet,B. and
            Polikarpov,I.
  TITLE     Involvement of the C terminus in intramolecular nitrogen channeling
            in glucosamine 6-phosphate synthase: evidence from a 1.6 A crystal
            structure of the isomerase domain
  JOURNAL   Structure 6 (8), 1047-1055 (1998)
   PUBMED   9739095
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013539.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF01380.27
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..353
                     /product="SIS domain-containing protein"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative
                     metabolic process [Evidence IEA]"
                     /calculated_mol_wt=38956
     Region          4..335
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
     Region          39..164
                     /region_name="SIS_GlmS_GlmD_1"
                     /note="SIS (Sugar ISomerase) domain repeat 1 found in
                     Glucosamine 6-phosphate synthase (GlmS) and
                     Glucosamine-6-phosphate deaminase (GlmD). The SIS domain
                     is found in many phosphosugar isomerases and phosphosugar
                     binding proteins. GlmS contains a N-terminal...; cd05008"
                     /db_xref="CDD:240141"
     Site            order(45..46,56..57,60..61,68,70,74,77,99)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:240141"
     Site            order(47..48,92..94)
                     /site_type="active"
                     /db_xref="CDD:240141"
ORIGIN      
        1 mhvedymnet pacllamltq tredlwqaak altergvtri iltgsgtsyh galtarsfmq
       61 qwcglpvdvy wpfllddsal tlsdkalvig isqgggslst laameraraa ghltasmage
      121 apavidraad lvltvpcgee ragaktkgyh ctilnlmllg lavasrqrrl sdeerkallv
      181 rmdttfnhlp tlieasqawv lnharplids adirltgpar lfgtvqegal kmletlrcpv
      241 agyefeefih giynafders tlimldpfpd erqdrlaeil ggwtqhiyri gpqvenngkn
      301 mpfafindpd favfeyiipl qmvcarlppv kgidpaipkd phfhqkmksk qln