MULTISPECIES: mechanosensitive ion channel family protein

LOCUS       WP_002892943             414 aa            linear   BCT 31-DEC-2024
            [Klebsiella].
ACCESSION   WP_002892943
VERSION     WP_002892943.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 414)
  AUTHORS   Malcolm,H.R. and Maurer,J.A.
  TITLE     The mechanosensitive channel of small conductance (MscS)
            superfamily: not just mechanosensitive channels anymore
  JOURNAL   Chembiochem 13 (14), 2037-2043 (2012)
   PUBMED   22915507
REFERENCE   2  (residues 1 to 414)
  AUTHORS   Haswell,E.S., Phillips,R. and Rees,D.C.
  TITLE     Mechanosensitive channels: what can they do and how do they do it?
  JOURNAL   Structure 19 (10), 1356-1369 (2011)
   PUBMED   22000509
REFERENCE   3  (residues 1 to 414)
  AUTHORS   Pivetti,C.D., Yen,M.R., Miller,S., Busch,W., Tseng,Y.H., Booth,I.R.
            and Saier,M.H. Jr.
  TITLE     Two families of mechanosensitive channel proteins
  JOURNAL   Microbiol Mol Biol Rev 67 (1), 66-85 (2003)
   PUBMED   12626684
REFERENCE   4  (residues 1 to 414)
  AUTHORS   Martinac,B.
  TITLE     Mechanosensitive channels in prokaryotes
  JOURNAL   Cell Physiol Biochem 11 (2), 61-76 (2001)
   PUBMED   11275684
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11430441
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..414
                     /product="mechanosensitive ion channel family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46228
     Region          74..396
                     /region_name="MscS"
                     /note="Small-conductance mechanosensitive channel [Cell
                     wall/membrane/envelope biogenesis]; COG0668"
                     /db_xref="CDD:440432"
ORIGIN      
        1 mqelisqiaa lgieitptrs lmiifgiilf tavvvhlilh kvvlrafekr alasshlwlq
       61 iitqnklfhr laftlqgiiv nvqavlwlqk gseaaeiltt vaqlwvmiya mlsffslldv
      121 ilklaqkfpa asqlplkgif qgiklvtaii igiliislli gqspailisg lgamaavlml
      181 vfkdpilglv agiqlsandm lklgdwlemp kygadgavid iglttvkvrn wdntittipt
      241 wslvsdsfkn wsgmsasggr rikrslnidt tsihfldeqe qqrlirakll kpymdsrhee
      301 isawnqqyag eqsvlnerrm tnvgtfrayl qeylrhhpri rqdmtlmvrq lapdanglpi
      361 eiycftntvv waeyegiqad ifdhvfavvd efglrihqtp tgndiraltg afsr