MULTISPECIES: M20 aminoacylase family protein [Klebsiella].

LOCUS       WP_002892704             392 aa            linear   BCT 21-MAR-2023
ACCESSION   WP_002892704
VERSION     WP_002892704.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Lindner,H.A., Lunin,V.V., Alary,A., Hecker,R., Cygler,M. and
            Menard,R.
  TITLE     Essential roles of zinc ligation and enzyme dimerization for
            catalysis in the aminoacylase-1/M20 family
  JOURNAL   J Biol Chem 278 (45), 44496-44504 (2003)
   PUBMED   12933810
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of metallopeptidases
  JOURNAL   Methods Enzymol 248, 183-228 (1995)
   PUBMED   7674922
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10145370
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..392
                     /product="M20 aminoacylase family protein"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /calculated_mol_wt=41977
     Region          14..389
                     /region_name="M20_Acy1-like"
                     /note="M20 Peptidase aminoacylase 1 subfamily; cd05666"
                     /db_xref="CDD:349916"
     Site            order(103,105,139,165,365)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:349916"
     Site            order(188,210..211,215,218,221,238..244,248..249,251,
                     257..259)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:349916"
ORIGIN      
        1 msdyvipeik ateaemisir hylhanpels leefntselv askltewgyq vtrglgktgv
       61 vgslskgdsp rtiglradmd alpieettgl pwastapgkm hacghdghtt illaaakyia
      121 spacqfngtv hlifqpaeea iggadlmikd glfeqfpcer ifglhnmpgl pvgklgfyag
      181 nfmasadtvk ititgygghg ahpertvdpi vagaalvmal qsivarnvpp getavvsvgt
      241 fqagiasnvi pesavmelsv ramkqeirdl likrihelad ftaksygass vvevydsypv
      301 ltnspeetdf aralalevfg regvlesvsp mnasedfafm lrerpgsyfl lgngekgekg
      361 gcmvhnpgyd fnddiitiga tlfarlvekh cr