MULTISPECIES: MFS transporter [Klebsiella].

LOCUS       WP_002892200             406 aa            linear   BCT 25-MAR-2023
ACCESSION   WP_002892200
VERSION     WP_002892200.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 406)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024721
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..406
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43187
     Region          30..398
                     /region_name="MFS_FsR"
                     /note="Fosmidomycin resistance protein of the Major
                     Facilitator Superfamily of transporters; cd17478"
                     /db_xref="CDD:341031"
     Site            order(37..38,41..42,45,77,127..128,130..132,135,154,
                     157..158,161,236,239..240,243..245,248,276,280,328..329,
                     333,337,352,355..356,359..360,363)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341031"
ORIGIN      
        1 mttnqsaqpl sgpaappqka rtsfgilgai slshllndmi qslilaiypl lqaefsltfv
       61 qigmitltfq ltsslfqpvi gyitdkrsmp wslpvgmcft lcglillala gsfgmvllaa
      121 alvgtgssvf hpessrvarm asggrhglaq slfqvggnfg sslgpllaav iiapygkgnv
      181 awfvlaalla ivvlsqisrw yaaqhrmnkg kpkpaivnpl prkkvilavg illmlifsky
      241 fymasissyy tfylmhkfgl tvqnaqlhlf aflfavaagt viggpvgdki grkyviwgsi
      301 lgvapftlvl pyaslewtgi ltviigfila safsailvya qellpgrigm vsglffgfaf
      361 gmgglgaavl glladhtsid lvykicaflp llgfltiflp dnrqka