MULTISPECIES: ferrochelatase [Klebsiella].

LOCUS       WP_002892189             320 aa            linear   BCT 24-OCT-2022
ACCESSION   WP_002892189
VERSION     WP_002892189.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Burden,A.E., Wu,C., Dailey,T.A., Busch,J.L., Dhawan,I.K.,
            Rose,J.P., Wang,B. and Dailey,H.A.
  TITLE     Human ferrochelatase: crystallization, characterization of the
            [2Fe-2S] cluster and determination that the enzyme is a homodimer
  JOURNAL   Biochim Biophys Acta 1435 (1-2), 191-197 (1999)
   PUBMED   10561552
REFERENCE   2  (residues 1 to 320)
  AUTHORS   Miyamoto,K., Kanaya,S., Morikawa,K. and Inokuchi,H.
  TITLE     Overproduction, purification, and characterization of
            ferrochelatase from Escherichia coli
  JOURNAL   J Biochem 115 (3), 545-551 (1994)
   PUBMED   8056770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00109.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..320
                     /gene="hemH"
     Protein         1..320
                     /product="ferrochelatase"
                     /EC_number="4.98.1.1"
                     /GO_function="GO:0004325 - ferrochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=35656
     Region          5..315
                     /region_name="HemH"
                     /note="Protoheme ferro-lyase (ferrochelatase) [Coenzyme
                     transport and metabolism]; COG0276"
                     /db_xref="CDD:440045"
ORIGIN      
        1 mhqtktgill anlgtpdapt pgavkrylrq flsdkrvvdt srllwwpllr gvilpirspr
       61 vaklyqsvwm eegsplmvys rrqqqalaar lpdtpvalgm sygspslasa vddllaqgve
      121 hivvlplypq yscstvaavw delarilakk raipgisfir dyaehpdyih alaasvrasf
      181 avhgepdlll lsyhgipqry anqgddypqr crdttrelvs alglppervm mtfqsrfgre
      241 pwltpytdet lkmlgekgtk hiqvlcpgfa adcletleei avqnreifle aggkqyeyip
      301 alnadaahie mmvnltapyr