MULTISPECIES: 1-deoxy-D-xylulose-5-phosphate synthase [Klebsiella].

LOCUS       WP_002891360             620 aa            linear   BCT 28-FEB-2022
ACCESSION   WP_002891360
VERSION     WP_002891360.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 620)
  AUTHORS   Lois,L.M., Campos,N., Putra,S.R., Danielsen,K., Rohmer,M. and
            Boronat,A.
  TITLE     Cloning and characterization of a gene from Escherichia coli
            encoding a transketolase-like enzyme that catalyzes the synthesis
            of D-1-deoxyxylulose 5-phosphate, a common precursor for
            isoprenoid, thiamin, and pyridoxol biosynthesis
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2105-2110 (1998)
   PUBMED   9482846
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00204.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..620
                     /gene="dxs"
     Protein         1..620
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=67199
     Region          7..620
                     /region_name="Dxs"
                     /note="Deoxyxylulose-5-phosphate synthase [Coenzyme
                     transport and metabolism, Lipid transport and metabolism];
                     COG1154"
                     /db_xref="CDD:440768"
ORIGIN      
        1 msfdiakypt lalvdstqel rllpkeslpk lcdelrryll dsvsrssghf asglgtvelt
       61 valhyvyntp fdrliwdvgh qayphkiltg rrdkigtirq kgglhpfpwr geseydvlsv
      121 ghsstsisag igvaiaaake dkqrravcvi gdgaitagma feamnhagdi kpdllvvlnd
      181 nemsisenvg alnnhlaqll sgklystlre ggkkvfsgvp pikellkrte ehikgmvvpg
      241 tlfeelgfny igpvdghdvl glvstlknmr dlkgpqflhi mtkkgrgyep aekdpitfha
      301 vpkfdhtsgv lpkssgglps yskifgdwlc etaakdnklm aitpamregs gmvefskkfp
      361 dryfdvaiae qhavtfaagl aigdykpvva iystflqray dqvihdvaiq klpvlfaidr
      421 agivgadgqt hqgafdlsfl rcipdmvvmt psdenecrqm lytgyhysng pcavryprgs
      481 gtgatlepla slpigkgvvk rqgekiailn fgtllpeaaa vadklnatlv dmrfvkpldt
      541 alilqlageh dalvtleena imggagsgvn evlmahrrav pvlniglpdy fipqgtqeei
      601 radlgldaag ieakirdwla