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MULTISPECIES: helix-turn-helix transcriptional regulator


LOCUS       WP_002890405             231 aa            linear   BCT 24-DEC-2024
            [Klebsiella].
ACCESSION   WP_002890405
VERSION     WP_002890405.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 231)
  AUTHORS   Keller,L.M. and Weber-Ban,E.
  TITLE     An emerging class of nucleic acid-sensing regulators in bacteria:
            WYL domain-containing proteins
  JOURNAL   Curr Opin Microbiol 74, 102296 (2023)
   PUBMED   37027901
REFERENCE   2  (residues 1 to 231)
  AUTHORS   Makarova,K.S., Anantharaman,V., Grishin,N.V., Koonin,E.V. and
            Aravind,L.
  TITLE     CARF and WYL domains: ligand-binding regulators of prokaryotic
            defense systems
  JOURNAL   Front Genet 5, 102 (2014)
   PUBMED   24817877
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 231)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   4  (residues 1 to 231)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   5  (residues 1 to 231)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457199
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..231
                     /product="helix-turn-helix transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=26704
     Region          2..>231
                     /region_name="YobV"
                     /note="Predicted DNA-binding transcriptional regulator
                     YobV, contains HTH and WYL domains [Transcription];
                     COG2378"
                     /db_xref="CDD:441945"
ORIGIN      
        1 mtrradrlfq ivqilrgrrl ttaallaerl gvsertvyrd irdlslsgvp vegeagsgyr
       61 llagydlppl mlttkeseam iaairllktw ggealsqsle saqekmlail pearrrqaeq
      121 trlfapdlga hryakthfdv ihqavsnqqv lqlhyqdesg qvtwrevlpl glffwgerwl
      181 lvawcelrnd yrnfrldrcl evrrterrfs ecadrslsdf lrkvrcevre k