MULTISPECIES: tRNA guanosine(34) transglycosylase Tgt [Klebsiella].

FASTA View on NCBI
LOCUS       WP_002890395             375 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002890395
VERSION     WP_002890395.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Kittendorf,J.D., Sgraja,T., Reuter,K., Klebe,G. and Garcia,G.A.
  TITLE     An essential role for aspartate 264 in catalysis by tRNA-guanine
            transglycosylase from Escherichia coli
  JOURNAL   J Biol Chem 278 (43), 42369-42376 (2003)
   PUBMED   12909636
REFERENCE   2  (residues 1 to 375)
  AUTHORS   Xie,W., Liu,X. and Huang,R.H.
  TITLE     Chemical trapping and crystal structure of a catalytic tRNA guanine
            transglycosylase covalent intermediate
  JOURNAL   Nat Struct Biol 10 (10), 781-788 (2003)
   PUBMED   12949492
  REMARK    Erratum:[Nat Struct Biol. 2004 Jul;11(7):678]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00430.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..375
                     /gene="tgt"
     Protein         1..375
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /EC_number="2.4.2.29"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008479 - queuine tRNA-ribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence
                     IEA]"
                     /calculated_mol_wt=42437
     Region          1..368
                     /region_name="Tgt"
                     /note="Queuine/archaeosine tRNA-ribosyltransferase
                     [Translation, ribosomal structure and biogenesis];
                     COG0343"
                     /db_xref="CDD:440112"
ORIGIN      
        1 mkfeldttdg rarrgrlvfe rgvvetpafm pvgtygtvkg mtpeeveatg aqiilgntfh
       61 lwlrpgqeim klhgdlhdfm qwkgpiltds ggfqvfslgd irkiteqgvh frnpingdpi
      121 fldpeksmei qydlgsdivm ifdectpypa dwdyakrsme mslrwakrsr drfdslgnkn
      181 alfgiiqgsv yedlrdisvk glveigfdgy avgglavgep kedmhrileh vcpqipadkp
      241 rylmgvgkpe dlvegvrrgi dmfdcvmptr narnghlfvt dgvvkirnak hksdtaplda
      301 ecdcytcrny sraylhhldr cneilgarln tihnlryyqr lmaglrkaie egklesfvtd
      361 fyqrqgrtvp plnvd