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MULTISPECIES: tRNA


LOCUS       WP_002889441             235 aa            linear   BCT 28-FEB-2022
            (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
            [Klebsiella].
ACCESSION   WP_002889441
VERSION     WP_002889441.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 235)
  AUTHORS   Forouhar,F., Kuzin,A., Seetharaman,J., Lee,I., Zhou,W.,
            Abashidze,M., Chen,Y., Yong,W., Janjua,H., Fang,Y., Wang,D.,
            Cunningham,K., Xiao,R., Acton,T.B., Pichersky,E., Klessig,D.F.,
            Porter,C.W., Montelione,G.T. and Tong,L.
  TITLE     Functional insights from structural genomics
  JOURNAL   J Struct Funct Genomics 8 (2-3), 37-44 (2007)
   PUBMED   17588214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00104.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..235
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..235
                     /gene="tsaA"
     Protein         1..235
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence
                     IEA]"
                     /calculated_mol_wt=26134
     Region          4..163
                     /region_name="TrmO"
                     /note="tRNA (Thr-GGU) A37 N6-methylase [Translation,
                     ribosomal structure and biogenesis]; COG1720"
                     /db_xref="CDD:441326"
     Site            order(9,47..49,51,58,62,87..92,96,98,100,133..138)
                     /site_type="other"
                     /note="homodimer interaction site [polypeptide binding]"
                     /db_xref="CDD:187753"
     Site            order(61,63..64,92,100,102,125,130)
                     /site_type="active"
                     /note="cofactor binding site [active]"
                     /db_xref="CDD:187753"
     Region          159..223
                     /region_name="TrmO_C"
                     /note="TrmO C-terminal domain; pfam18389"
                     /db_xref="CDD:465738"
ORIGIN      
        1 msafqfaqig virspykekf avprqpglvk hgggelhlva pynqadavrg lesfshlwil
       61 fvfhqtmegg wrptvrpprl ggnarmgvfa trstfrpnpi gmslvelkgi rcqkdqvile
      121 lgsldlvdgt pvvdikpylp faealpdasa syaqqaplag mnvsftpeid aqlltlekry
      181 phikafirev laqdprpayr keeqagktya vwlldfnvrw rvtasgfevf alear