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LOCUS WP_002889208 850 aa linear BCT 01-JUL-2024 [Klebsiella]. ACCESSION WP_002889208 VERSION WP_002889208.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 850) AUTHORS Charpentier,X., Chalut,C., Remy,M.H. and Masson,J.M. TITLE Penicillin-binding proteins 1a and 1b form independent dimers in Escherichia coli JOURNAL J Bacteriol 184 (13), 3749-3752 (2002) PUBMED 12057973 REFERENCE 2 (residues 1 to 850) AUTHORS Chalut,C., Remy,M.H. and Masson,J.M. TITLE Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli JOURNAL J Bacteriol 181 (9), 2970-2972 (1999) PUBMED 10217796 REFERENCE 3 (residues 1 to 850) AUTHORS Vollmer,W., von Rechenberg,M. and Holtje,J.V. TITLE Demonstration of molecular interactions between the murein polymerase PBP1B, the lytic transglycosylase MltA, and the scaffolding protein MipA of Escherichia coli JOURNAL J Biol Chem 274 (10), 6726-6734 (1999) PUBMED 10037771 REFERENCE 4 (residues 1 to 850) AUTHORS Zijderveld,C.A., Aarsman,M.E., den Blaauwen,T. and Nanninga,N. TITLE Penicillin-binding protein 1B of Escherichia coli exists in dimeric forms JOURNAL J Bacteriol 173 (18), 5740-5746 (1991) PUBMED 1885547 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF007061.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK09506 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..850 /organism="Klebsiella" /db_xref="taxon:570" gene 1..850 /gene="mrcB" Protein 1..850 /product="bifunctional glycosyl transferase/transpeptidase" /EC_number="2.4.99.28" /GO_component="GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]" /GO_function="GO:0008658 - penicillin binding [Evidence IEA]" /GO_function="GO:0008955 - peptidoglycan glycosyltransferase activity [Evidence IEA]" /GO_process="GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]" /GO_process="GO:0046677 - response to antibiotic [Evidence IEA]" /calculated_mol_wt=94897 Region 1..849 /region_name="mrcB" /note="bifunctional glycosyl transferase/transpeptidase; Reviewed; PRK09506" /db_xref="CDD:236544" ORIGIN 1 magddrepig rkgrpsrptk qkvtrrrvre edyddeyddd dyedekpvpr kakgkggkpr 61 rkrswlwllv klgivfavli aaygvyldqk irsridgkvw elpaavygrm vnlepdmqis 121 knemvrllna tqyrqvsamt rpgeytvqan siemirrpfd fpdskegqvr arltfdgdhl 181 etienmdnnr qfgffrldpr litmlqspng eqrlfvkrsg fpdllvdtll atedrhfyeh 241 dgislysigr avlanltagr tvqgastltq qlvknlflss ersywrkane aymalivdar 301 yskdrilely mnevylgqsg dneirgfpla slyyfgrpve elsldqqall vgmvkgasvy 361 npwrnpklal errnlvlrll qqqqvidqel ydmlsarplg vqprggvisp qpafmqmvrq 421 elqaklgdkv kdlsgvkift tfdsvaqdaa ekaasegipv lkkqrkladl etamvvvdrf 481 tgevramvgg aepqfagynr amqarrsigs lakpatylta lsqpnqyrln twiadapvti 541 rlsngqtwsp qnddrrfsgq vmlvdaltrs mnvptvnlgm alglpavvdt wtklgapknq 601 lnavpsmllg alnltpieva qafqtiasgg nraplsalrs viaedgtvly qsypqaerav 661 paqaaymtlw tmqqvvqrgt grqlgakypg lhlagktgtt nnnvdtwfag idgsqvtitw 721 vgrdnnqptk lygasgamsi yqrylanqtp tplvltvped vvdmgvdsng nfvcsggmrs 781 lpvwttqpda lcrqgemmqq qqlqqqeakn pfnqsgqqpp pqqqqqqqpp kqqeksdgva 841 gwikdmfgsn