MULTISPECIES: pantoate--beta-alanine ligase [Klebsiella].

LOCUS       WP_002888835             284 aa            linear   BCT 27-DEC-2023
ACCESSION   WP_002888835
VERSION     WP_002888835.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 284)
  AUTHORS   Chakrabarti,K.S., Thakur,K.G., Gopal,B. and Sarma,S.P.
  TITLE     X-ray crystallographic and NMR studies of pantothenate synthetase
            provide insights into the mechanism of homotropic inhibition by
            pantoate
  JOURNAL   FEBS J 277 (3), 697-712 (2010)
   PUBMED   20059543
REFERENCE   2  (residues 1 to 284)
  AUTHORS   Zheng,R. and Blanchard,J.S.
  TITLE     Steady-state and pre-steady-state kinetic analysis of Mycobacterium
            tuberculosis pantothenate synthetase
  JOURNAL   Biochemistry 40 (43), 12904-12912 (2001)
   PUBMED   11669627
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00018.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..284
                     /gene="panC"
     Protein         1..284
                     /product="pantoate--beta-alanine ligase"
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=31401
     Region          1..281
                     /region_name="PanC"
                     /note="Panthothenate synthetase [Coenzyme transport and
                     metabolism]; COG0414"
                     /db_xref="CDD:440183"
ORIGIN      
        1 mliiesvlll rqhirrlrqe gkrialvptm gnlhdghmkl vdeakasadv vvvsifvnpm
       61 qfdrvddlar yprtlqddce klnkrhvdfv faptpaevyp qgtegqtyvd vpglstmleg
      121 asrpghfrgv stivsklfnl vqpdvacfge kdfqqlalir kmvadmgydi eiigvpivra
      181 kdglalssrn gyltadqrki apglykvlsa vaeklaagdr qldeiiaiae qelnekgfra
      241 ddiqirdadt lleltdasqr avilmaawlg qarlidnriv tlaq