Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: hypoxanthine phosphoribosyltransferase [Klebsiella].


LOCUS       WP_002888819             178 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002888819
VERSION     WP_002888819.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 178)
  AUTHORS   Lee,C.C., Craig,S.P. 3rd and Eakin,A.E.
  TITLE     A single amino acid substitution in the human and a bacterial
            hypoxanthine phosphoribosyltransferase modulates specificity for
            the binding of guanine
  JOURNAL   Biochemistry 37 (10), 3491-3498 (1998)
   PUBMED   9521670
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01203.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..178
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..178
                     /gene="hpt"
     Protein         1..178
                     /product="hypoxanthine phosphoribosyltransferase"
                     /EC_number="2.4.2.8"
                     /GO_process="GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /calculated_mol_wt=19991
     Region          1..178
                     /region_name="PRK15423"
                     /note="hypoxanthine phosphoribosyltransferase;
                     Provisional"
                     /db_xref="CDD:185321"
     Site            order(42,44,99..101,103..107,131)
                     /site_type="active"
                     /db_xref="CDD:206754"
ORIGIN      
        1 mkhtvevmip eseikariae lgrqinehyq nsgsemvlvg llrgsfmfma dlcrevqvph
       61 evdfmtassy gsgmsttrdv kilkdldedi rgkdvlived iidsgntlsk vreilslrep
      121 kslaictlld kpsrrevnvp veyvgfaipd efvvgygidy aqryrhlpyi gkvtllde