MULTISPECIES: 2-isopropylmalate synthase [Klebsiella].

LOCUS       WP_002888490             523 aa            linear   BCT 13-MAY-2021
ACCESSION   WP_002888490
VERSION     WP_002888490.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002084.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00915
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..523
                     /gene="leuA"
     Protein         1..523
                     /product="2-isopropylmalate synthase"
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=57413
     Region          1..512
                     /region_name="PRK00915"
                     /note="2-isopropylmalate synthase; Validated"
                     /db_xref="CDD:234864"
     Site            order(13..14,17,44,75,97,139,141,169,171,202,204)
                     /site_type="active"
                     /db_xref="CDD:163678"
     Site            order(13..14,44)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     Site            order(202,204)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:163678"
ORIGIN      
        1 msqqviifdt tlrdgeqalq aslsvkeklq ialalermgv dvmevgfpvs spgdfesvqt
       61 itrtiknsrv calarcvekd idvaaeslkv aeafrihtfi atspmhiatk lrstldevie
      121 raiymvkrar nytddvefsc edagrtpiad larvveaain agattinipd tvgytmpfey
      181 aniisglydr vpnidkaiis vhthddlgia vgnalaavha garqvegamn gigeragnca
      241 leevimaikv rkdimnvhtn inhheiwrts qtvsqicnmp ipankaivgt gafahssgih
      301 qdgvlknren yeimtpesig lnqvqlnlts rsgraavkhr meemgyqesd ynldhlydaf
      361 lkladkkgqv fdydlealaf inkqqeepeh frldyfnvqs gssdiatasi klvcgdeikt
      421 eaangngpvd aiyqainrvt dynielvkyg lsakghgkda lgqvdivvdy ngrrfhgvgl
      481 atdivessak amvhvlnniw raaevekelq rkaqnkennk etv