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MULTISPECIES: 3-isopropylmalate dehydrogenase [Klebsiella].


LOCUS       WP_002888487             363 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002888487
VERSION     WP_002888487.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 363)
  AUTHORS   Dean,A.M. and Golding,G.B.
  TITLE     Protein engineering reveals ancient adaptive replacements in
            isocitrate dehydrogenase
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3104-3109 (1997)
   PUBMED   9096353
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00169.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..363
                     /gene="leuB"
     Protein         1..363
                     /product="3-isopropylmalate dehydrogenase"
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39371
     Region          3..362
                     /region_name="PRK00772"
                     /note="3-isopropylmalate dehydrogenase; Provisional"
                     /db_xref="CDD:234832"
ORIGIN      
        1 msknyhiavl pgdgigpevm nqamkvleav rqrfamhitt sqydvggaai drqgtplpqa
       61 tvagceqada ilfgsvggpk wehlppaeqp ergallplrk hfklfsnlrp aklyqgleef
      121 cplradiaan gfdilcvrel tggiyfgqpk gregsgqhek afdtevyhrf eieriariaf
      181 esarkrrhkv tsidkanvlq ssilwreivs eigkeypdve lahmyidnat mqlikdpsqf
      241 dvllcsnlfg dilsdecami tgsmgmlpsa slneqgfgly epaggsapdi agknianpia
      301 qilslalllr ysldadeaat aienainral eegvrtgdla rgtaavstde mgdiiaryva
      361 egv