MULTISPECIES: 3-isopropylmalate dehydratase large subunit

LOCUS       WP_002888484             466 aa            linear   BCT 01-JUL-2024
            [Klebsiella].
ACCESSION   WP_002888484
VERSION     WP_002888484.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..466
                     /gene="leuC"
     Protein         1..466
                     /product="3-isopropylmalate dehydratase large subunit"
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=49740
     Region          1..466
                     /region_name="PRK05478"
                     /note="3-isopropylmalate dehydratase large subunit"
                     /db_xref="CDD:235490"
     Site            order(33,36,128..129,411,430,435)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:153133"
     Site            order(130,347,407,410..411,429)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:153133"
ORIGIN      
        1 maktlyeklf dahvvyeaqn etpllyidrh lvhevtspqa fdglrahgrq vrqpgktfat
       61 mdhnvstqtk dinasgemar iqmqeliknc kefgvelydl nhpyqgivhv mgpeqgvtlp
      121 gmtivcgdsh tathgafgal afgigtseve hvlatqtlkq graktmkiev qgkaapgita
      181 kdivlaiigk tgsaggtghv vefcgeaird lsmegrmtlc nmaiemgaka glvapdettf
      241 nyvrgrlhap kgkdfddava ywktlktdda atfdtvvtlq aaeiapqvtw gtnpgqvisv
      301 tdnipdpasf sdpverasae kalvymglks gipltevaid kvfigsctns riedlraaae
      361 iakgrkvapg vqalvvpgsg pvkaqaeaeg ldkifieagf ewrlpgcsmc lamnndrlnp
      421 gercastsnr nfegrqgrgg rthlvspama aaaavtghfa dirnlk