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MULTISPECIES: type 3 dihydrofolate reductase [Klebsiella].


LOCUS       WP_002888320             159 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002888320
VERSION     WP_002888320.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008037.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10769
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..159
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..159
                     /gene="folA"
     Protein         1..159
                     /product="type 3 dihydrofolate reductase"
                     /GO_function="GO:0004146 - dihydrofolate reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=17834
     Region          1..159
                     /region_name="folA"
                     /note="type 3 dihydrofolate reductase; PRK10769"
                     /db_xref="CDD:182714"
     Site            order(5,22,27,57,94,100,113)
                     /site_type="other"
                     /note="folate binding site [chemical binding]"
                     /db_xref="CDD:238127"
     Site            order(7,14,44..46,64,95..98)
                     /site_type="other"
                     /note="NADP+ binding site [chemical binding]"
                     /db_xref="CDD:238127"
ORIGIN      
        1 misliaalav drvigmenam pwnlpadlaw fkrntlnkpv vmgrltwesi grplpgrkni
       61 visskpgsdd rvqwvssvee aiaacgdvee imvigggrvy eqflpkaqkl ylthidaeve
      121 gdthfpdydp dewesvfsef hdadaqnshs ycfeilerr