MULTISPECIES: bifunctional aspartate kinase/homoserine

LOCUS       WP_002887848             820 aa            linear   BCT 20-NOV-2023
            dehydrogenase I [Klebsiella].
ACCESSION   WP_002887848
VERSION     WP_002887848.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 820)
  AUTHORS   Theze,J., Margarita,D., Cohen,G.N., Borne,F. and Patte,J.C.
  TITLE     Mapping of the structural genes of the three aspartokinases and of
            the two homoserine dehydrogenases of Escherichia coli K-12
  JOURNAL   J. Bacteriol. 117 (1), 133-143 (1974)
   PUBMED   4148765
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006959.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09436
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..820
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..820
                     /gene="thrA"
     Protein         1..820
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /GO_function="GO:0004072 - aspartate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0008652 - cellular amino acid biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009067 - aspartate family amino acid
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=88390
     Region          1..820
                     /region_name="thrA"
                     /note="bifunctional aspartokinase I/homoserine
                     dehydrogenase I; Provisional; PRK09436"
                     /db_xref="CDD:181856"
ORIGIN      
        1 mrvlkfggts vanaerflrv adilesnarq gqvatvlsap akitnhlvam iektiggqda
       61 lpniadaeri faellqglad aqpafplaql kafveqefaq ikhvlhgisl lgqcpdsvna
      121 alicrgekls iaimagllea rghkvsvinp vekllavghy lestvdiaes trriaasqip
      181 adhmilmagf tagnekgelv vlgrngsdys aavlaaclra dcceiwtdvd gvytcdprqv
      241 pdarllksms yqeamelsyf gakvlhprti apiaqfqipc likntgnpqa pgtligasrd
      301 eddlpvkgis nlnnmamfnv sgpgmkgmvg maarvfatms ragisvvlit qssseysisf
      361 cvpqsdcara kramedefyl elkegllepl aimerlaiis vvgdgmrtlr gisakffaal
      421 araninivai aqgssersis vvvsnddatt gvrvthqmlf ntdqvievfv igvggvggal
      481 leqikrqqgw lknkhidlrv cgvansqall tsvhglnlen wsaelaeake pfnlgrlirl
      541 vkeyhllnpv ivdctssqav adqyadflre gfhvvtpnkk antssldyyh qlrhaasssr
      601 rkflydtnvg aglpvienlq nllnagdelr hfsgilsgsl sfifgkldeg vsfsaatama
      661 remgytepdp rddlsgvdva rkllilaret greleladii vesalppdfd asgdvetfma
      721 rlpslddgfa srvakardeg kvlryvgnie edgtcrvkia avdgndplfk vkngenalaf
      781 yshyyqplpl vlrgygagnd vtaagvfadl lrtlswklgv