MULTISPECIES: thymidine phosphorylase [Klebsiella].

FASTA View on NCBI
LOCUS       WP_002887787             440 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_002887787
VERSION     WP_002887787.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 440)
  AUTHORS   Schinazi,R.F., Peck,A. and Sommadossi,J.P.
  TITLE     Substrate specificity of Escherichia coli thymidine phosphorylase
            for pyrimidine nucleosides with anti-human immunodeficiency virus
            activity
  JOURNAL   Biochem Pharmacol 44 (2), 199-204 (1992)
   PUBMED   1322661
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02643.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..440
                     /gene="deoA"
     Protein         1..440
                     /product="thymidine phosphorylase"
                     /EC_number="2.4.2.4"
                     /GO_function="GO:0009032 - thymidine phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=46914
     Region          1..440
                     /region_name="deoA"
                     /note="thymidine phosphorylase; Reviewed; PRK05820"
                     /db_xref="CDD:180276"
ORIGIN      
        1 mflaqeiirk krdgqalsde eirffingir dntisegqia alamtiffhd msmpervslt
       61 mamrdsgtvl dwkslnlngp ivdkhstggv gdvtslmlgp mvaacggyvp misgrglght
      121 ggtldkleai pgfdifpddn rfreiikdvg vaiigqtssl apadkrfyat rditatvdsi
      181 plitasilak klaegldalv mdvkvgsgaf mptyelsaal aeaivgvang agvrttallt
      241 dmnqvlassa gnavevreav qfltgeyrnp rlfdvtmalc vemlisgkla addaearakl
      301 qavldngkaa evfgrmvaaq kgpsdfveny anylptamls kavyadtegf isamdtralg
      361 mavvsmgggr rqasdtidys vgftemarlg drvdgqrpla vihakdensw qeaakavkaa
      421 iklddkapei tptvyrrite