MULTISPECIES: SIS domain-containing protein [Klebsiella].

LOCUS       WP_002887615             336 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_002887615
VERSION     WP_002887615.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 336)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454870
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..336
                     /product="SIS domain-containing protein"
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=38361
     Region          18..333
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
     Region          38..153
                     /region_name="SIS_1"
                     /note="A subgroup of the SIS domain. SIS (Sugar ISomerase)
                     domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. SIS domains are also found
                     in proteins that regulate the expression of genes involved
                     in synthesis of phosphosugars; cd05710"
                     /db_xref="CDD:240214"
     Site            order(46,91)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:240214"
ORIGIN      
        1 mlgfnqdeyl tsareiiaar kqaetvaddi ydsgcsalff asvggslapm mainefakel
       61 tsvpvyleqa aelihrghkk lnkdavvvtl sksgdtkesv aiaewckaqg irvvaitrha
      121 dsplaaaasw hipmchkngv eyeymllywl ffrvifrhge fadyarfasq lellpenllq
      181 akrqfdprad siaaqyhdcd ymmwiggaem wgevylfsmc ileemqwkrt ksvssaeffh
      241 gtlellekev plflvkgegr cralderver faekitehlv vidprdypln giddafrwim
      301 apcvvstllv drlaahfehh tghdlnirry yrqfdy