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LOCUS WP_002887498 254 aa linear BCT 02-MAR-2025 [Klebsiella]. ACCESSION WP_002887498 VERSION WP_002887498.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 254) AUTHORS Pollard,J.R. and Bugg,T.D. TITLE Purification, characterisation and reaction mechanism of monofunctional 2-hydroxypentadienoic acid hydratase from Escherichia coli JOURNAL Eur J Biochem 251 (1-2), 98-106 (1998) PUBMED 9492273 REFERENCE 2 (residues 1 to 254) AUTHORS St-Louis,M. and Tanguay,R.M. TITLE Mutations in the fumarylacetoacetate hydrolase gene causing hereditary tyrosinemia type I: overview JOURNAL Hum Mutat 9 (4), 291-299 (1997) PUBMED 9101289 REFERENCE 3 (residues 1 to 254) AUTHORS Prieto,M.A., Diaz,E. and Garcia,J.L. TITLE Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster JOURNAL J Bacteriol 178 (1), 111-120 (1996) PUBMED 8550403 REFERENCE 4 (residues 1 to 254) AUTHORS Fernandez-Canon,J.M. and Penalva,M.A. TITLE Fungal metabolic model for human type I hereditary tyrosinaemia JOURNAL Proc Natl Acad Sci U S A 92 (20), 9132-9136 (1995) PUBMED 7568087 REFERENCE 5 (residues 1 to 254) AUTHORS Roper,D.I., Stringfellow,J.M. and Cooper,R.A. TITLE Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway JOURNAL Gene 156 (1), 47-51 (1995) PUBMED 7737515 REFERENCE 6 (residues 1 to 254) AUTHORS Roper,D.I. and Cooper,R.A. TITLE Purification, nucleotide sequence and some properties of a bifunctional isomerase/decarboxylase from the homoprotocatechuate degradative pathway of Escherichia coli C JOURNAL Eur J Biochem 217 (2), 575-580 (1993) PUBMED 8223600 REFERENCE 7 (residues 1 to 254) AUTHORS Harayama,S. and Rekik,M. TITLE Comparison of the nucleotide sequences of the meta-cleavage pathway genes of TOL plasmid pWW0 from Pseudomonas putida with other meta-cleavage genes suggests that both single and multiple nucleotide substitutions contribute to enzyme evolution JOURNAL Mol Gen Genet 239 (1-2), 81-89 (1993) PUBMED 8510667 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF013706.6 Evidence Source :: EMBL-EBI Source Identifier :: PF01557.23 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..254 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..254 /product="fumarylacetoacetate hydrolase family protein" /GO_function="GO:0003824 - catalytic activity [Evidence IEA]" /calculated_mol_wt=28505 Region <25..248 /region_name="PRK15203" /note="4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional" /db_xref="CDD:185125" ORIGIN 1 mkqariewqg qvrdvlvner dqvrlddgtv lkegefrwlp pangtlfalg lnyadhasel 61 efkppteplv fikapntftg hqqqsvrpdn veymhyeael vvvigktarr vseaeamdyv 121 agytvcndya irdylenyyr pnlrvksrdt ltpigpwivs keaipdphnl alrtwvngel 181 rqqgttadli fsipfliayl sefmtlqpgd miatgtpkgl sdvvpgdevi vevegvgrlv 241 nhiisqqaye etls