MULTISPECIES: HNH endonuclease [Klebsiella].

LOCUS       WP_002887060             212 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_002887060
VERSION     WP_002887060.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 212)
  AUTHORS   Nemeth,E., Kozisek,M., Schilli,G.K. and Gyurcsik,B.
  TITLE     Preorganization of the catalytic Zn(2+)-binding site in the HNH
            nuclease motif--A solution study
  JOURNAL   J Inorg Biochem 151, 143-149 (2015)
   PUBMED   25898772
REFERENCE   2  (residues 1 to 212)
  AUTHORS   Veluchamy,A., Mary,S., Acharya,V., Mehta,P., Deva,T. and
            Krishnaswamy,S.
  TITLE     HNHDb: a database on pattern based classification of HNH domains
            reveals functional relevance of sequence patterns and domain
            associations
  JOURNAL   Bioinformation 4 (2), 80-83 (2009)
   PUBMED   20198175
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 212)
  AUTHORS   Mehta,P., Katta,K. and Krishnaswamy,S.
  TITLE     HNH family subclassification leads to identification of commonality
            in the His-Me endonuclease superfamily
  JOURNAL   Protein Sci 13 (1), 295-300 (2004)
   PUBMED   14691243
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11459846
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..212
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..212
                     /product="HNH endonuclease"
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=23403
     Region          107..209
                     /region_name="COG3183"
                     /note="Predicted restriction endonuclease, HNH family
                     [Defense mechanisms]"
                     /db_xref="CDD:442416"
ORIGIN      
        1 mkklpdhlsr eciiaairay dagvahqfks arlyeiefeg rrypskaivg laatlatgte
       61 ftpadfsggi kskcvrllld qgftiasqga gddevalfpd egqttmefve gaamqvvvnr
      121 yerdrqarqa alrlhgcrcq vcgldmasry geigqgfihi hhliplagik qdyrlnpetd
      181 lipvcpncha mlhrrdppft peelkarlrp ad