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LOCUS WP_002886952 951 aa linear BCT 01-MAR-2021 ACCESSION WP_002886952 VERSION WP_002886952.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 951) AUTHORS Fukunaga,R. and Yokoyama,S. TITLE Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain JOURNAL J. Biol. Chem. 280 (33), 29937-29945 (2005) PUBMED 15970591 REFERENCE 2 (residues 1 to 951) AUTHORS Tardif,K.D. and Horowitz,J. TITLE Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase JOURNAL RNA 10 (3), 493-503 (2004) PUBMED 14970394 REFERENCE 3 (residues 1 to 951) AUTHORS Fukai,S., Nureki,O., Sekine,S., Shimada,A., Vassylyev,D.G. and Yokoyama,S. TITLE Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase JOURNAL RNA 9 (1), 100-111 (2003) PUBMED 12554880 REFERENCE 4 (residues 1 to 951) AUTHORS Hountondji,C., Lazennec,C., Beauvallet,C., Dessen,P., Pernollet,J.C., Plateau,P. and Blanquet,S. TITLE Crucial role of conserved lysine 277 in the fidelity of tRNA aminoacylation by Escherichia coli valyl-tRNA synthetase JOURNAL Biochemistry 41 (50), 14856-14865 (2002) PUBMED 12475234 REFERENCE 5 (residues 1 to 951) AUTHORS Fukai,S., Nureki,O., Sekine,S., Shimada,A., Tao,J., Vassylyev,D.G. and Yokoyama,S. TITLE Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase JOURNAL Cell 103 (5), 793-803 (2000) PUBMED 11114335 REFERENCE 6 (residues 1 to 951) AUTHORS Heck,J.D. and Hatfield,G.W. TITLE Valyl-tRNA synthetase gene of Escherichia coli K12. Primary structure and homology within a family of aminoacyl-TRNA synthetases JOURNAL J. Biol. Chem. 263 (2), 868-877 (1988) PUBMED 3275660 REFERENCE 7 (residues 1 to 951) AUTHORS Hartlein,M., Frank,R. and Madern,D. TITLE Nucleotide sequence of Escherichia coli valyl-tRNA synthetase gene valS JOURNAL Nucleic Acids Res. 15 (21), 9081-9082 (1987) PUBMED 3317277 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF004349.1 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK05729 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..951 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..951 /product="valine--tRNA ligase" /EC_number="6.1.1.9" /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0004832 - valine-tRNA ligase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_process="GO:0006438 - valyl-tRNA aminoacylation [Evidence IEA]" /calculated_mol_wt=108149 Region 1..949 /region_name="ValS" /note="Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; COG0525" /db_xref="CDD:440291" ORIGIN 1 mektynpqdi eqplyehwek qgyfkpngde sqesfcimip ppnvtgslhm ghafqqtimd 61 tmiryqrmqg kntlwqagtd hagiatqmvv erkiaaeegk trhdygrdaf idkiwqwkae 121 sggtitrqmr rlgnsvdwer erftmdegls navkevfvrl ykedliyrgk rlvnwdpklr 181 taisdleven reskgsmwhi rypladgakt adgkdylvva ttrpetllgd tgvavnpedp 241 rykdligkfv vlplvnrrip ivgdehadme kgtgcvkitp ahdfndyevg rrhqlpmini 301 ltfdgdires aevydtkgne sdvysseipa efqklerfaa rkavvaavda lglleeikph 361 dltvpygdrg gvviepmltd qwyvradvla kpaveaveng diqfvpkqye nmyfswmrdi 421 qdwcisrqlw wghripawyd ndgnvyvgrs edevrqennl sadvalrqde dvldtwfssa 481 lwtfstlgwp entdalrqfh ptsvmvsgfd iiffwiarmi mmtmhfikde ngkpqvpfkt 541 vymtglirdd egqkmskskg nvidpldmvd gitlpellek rtgnmmqpql adkirkrtek 601 qfpngiephg tdalrftlaa lastgrdinw dmkrlegyrn fcnklwnasr fvlmntedqd 661 cgfnggemvl sladrwiiae fnhtvkayre aldnfrfdia agilyeftwn qfcdwylelt 721 kpvmnggnea elrgtrhtlv tvlegllrla hpiipfitet iwqrvkaicg itadtimlqp 781 fpqydasqvd daaladtewl kqaivavrni raemniapgk plelllrgcs kdaerrvndn 841 rsfllnlarl esitvlpadd kgpvsvtkiv dgaellipma glinkedela rlakevakie 901 geigrieskl anegfvarap eaviakerek legyaeakak lieqqaviaa l