MULTISPECIES: LysR family transcriptional regulator [Klebsiella].

LOCUS       WP_002885085             293 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002885085
VERSION     WP_002885085.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 293)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 293)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 293)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444076
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..293
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33186
     Region          3..62
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..286
                     /region_name="PBP2_CidR"
                     /note="The C-terminal substrate binding domain of
                     LysR-like transcriptional regulator CidR, contains the
                     type 2 periplasmic binding fold; cd08438"
                     /db_xref="CDD:176129"
     Site            order(106..107,109..110,113,117,119..125,218..223,
                     229..230,232..233)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176129"
ORIGIN      
        1 mdirtlryfv evvrqqsftr aaeklfvtqp tiskmlknle delnctllir dgrkllltdt
       61 grvvfergqa ilgefsqles elsdinhlhk gvlrlgippm vgmlmaepis rfrqrypgve
      121 lkiaefgglt vqqavsngel dmamtalpve edssltilpl fnhplcvltp rtaewegkts
      181 lspaelashp lviyneefal sqqlmrlfae hdvkpriavr sgqwdflaam vqagigvail
      241 pepicqrldr qnfcwiplqs elrwelgmiw regvymsrsa eawltcskaf wle