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MULTISPECIES: NCS2 family permease [Klebsiella].


LOCUS       WP_002885079             449 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002885079
VERSION     WP_002885079.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 449)
  AUTHORS   Koukaki,M., Vlanti,A., Goudela,S., Pantazopoulou,A., Gioule,H.,
            Tournaviti,S. and Diallinas,G.
  TITLE     The nucleobase-ascorbate transporter (NAT) signature motif in UapA
            defines the function of the purine translocation pathway
  JOURNAL   J Mol Biol 350 (3), 499-513 (2005)
   PUBMED   15953615
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10789293
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..449
                     /product="NCS2 family permease"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /calculated_mol_wt=45533
     Region          10..444
                     /region_name="NCS2"
                     /note="Xanthine/guanine/uracil/vitamin C permease
                     GhxP/GhxQ, nucleobase:cation symporter 2 (NCS2) family
                     [Nucleotide transport and metabolism]; COG2252"
                     /db_xref="CDD:441853"
ORIGIN      
        1 mstpsartgg sldawfkisa rgstvrqeiv aglttflamv ysvivvpgml gkagfppaav
       61 fvstclvagv gslamglwan lpmaigcais ltaftafslv lgqqisipva lgavflmgvl
      121 ftvisatgir swilrnlpqg vahgtgigig lfllliaang vglviknpld glpvalgnfd
      181 sfpvvmslig laviiglekm kvpggillti igvsivglif dpnvhfsgif ampslsdgqg
      241 nsligsldiv galnpvvlps vlalvmtavf datgtirava gqanlldkdg qiinggkalt
      301 tdslssvfsg lvgaapaavy iesaagtaag gktgltavtv gvlfllilfl splsylvpay
      361 atapalmyvg llmlsnvaki dfndfvdama glitavfivl tcnivtgimi gfatlvigrl
      421 vsgewrklnl gtviiavalv vfyaggwai