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MULTISPECIES: bifunctional biotin--[acetyl-CoA-carboxylase]


LOCUS       WP_002883521             320 aa            linear   BCT 20-OCT-2023
            ligase/biotin operon repressor BirA [Enterobacterales].
ACCESSION   WP_002883521
VERSION     WP_002883521.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008849.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11886
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     gene            1..320
                     /gene="birA"
     Protein         1..320
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /EC_number="6.3.4.15"
                     /GO_function="GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /calculated_mol_wt=35301
     Region          2..320
                     /region_name="PRK11886"
                     /note="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /db_xref="CDD:237010"
     Site            order(89..91,112,115..118,121..124,132..134,172,176,178,
                     183,186,188,204..206,208)
                     /site_type="active"
                     /db_xref="CDD:319741"
     Site            183
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:319741"
ORIGIN      
        1 mkdhtipltl isiladgefh sgeqlgeqlg msraainkhi qtlrdwgvdv ftvpgkgysl
       61 pepihlldek kisqeidhgr vtvlpvidst nqylldrlde ltsgdacvae yqqagrgrrg
      121 rkwfspfgan lylsmywrle qgpaaaigls lvigiviaev lqqlgaeqvr vkwpndiylq
      181 drklsgilve ltgktgdaaq ivsgaginlv mrrvesdvvn qgwislqeag vvidrnllaa
      241 rlikelrlgl elfeqeglap ylprwekldn fihrpvklii gdkeiygisr gidaqgalll
      301 eqdgvikawv ggeislrsae