MULTISPECIES: UDP-N-acetylmuramate dehydrogenase

LOCUS       WP_002883510             342 aa            linear   BCT 21-APR-2021
            [Gammaproteobacteria].
ACCESSION   WP_002883510
VERSION     WP_002883510.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 342)
  AUTHORS   El Zoeiby,A., Sanschagrin,F. and Levesque,R.C.
  TITLE     Structure and function of the Mur enzymes: development of novel
            inhibitors
  JOURNAL   Mol. Microbiol. 47 (1), 1-12 (2003)
   PUBMED   12492849
REFERENCE   2  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     X-ray crystal structures of the S229A mutant and wild-type MurB in
            the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine
            at 1.8-A resolution
  JOURNAL   Biochemistry 36 (4), 806-811 (1997)
   PUBMED   9020778
REFERENCE   3  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     The structure of the substrate-free form of MurB, an essential
            enzyme for the synthesis of bacterial cell walls
  JOURNAL   Structure 4 (1), 47-54 (1996)
   PUBMED   8805513
REFERENCE   4  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     Crystallization and preliminary X-ray crystallographic studies of
            UDP-N-acetylenolpyruvylglucosamine reductase
  JOURNAL   Protein Sci. 3 (7), 1125-1127 (1994)
   PUBMED   7920261
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000755.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00046
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..342
                     /gene="murB"
     Protein         1..342
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /EC_number="1.3.1.98"
                     /GO_function="GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /calculated_mol_wt=37692
     Region          1..329
                     /region_name="murB"
                     /note="UDP-N-acetylmuramate dehydrogenase; PRK00046"
                     /db_xref="CDD:234593"
ORIGIN      
        1 mnhslkpwnt fgierfakti vraeteqqll sawqtaaaag eptlilgegs nvlflndyag
       61 tvilnrimgi evsetpeawr lhvgagenwh qlvqftlqha mpglenlali pgcagsspiq
      121 nigaygvelq rvceyvdcie letgrkqrls aaecrfgyrd sifkheyqdr yaivaiglsl
      181 aktwqpvlsy gdltrldpqt vtpqqvfdav chmrmtklpd pkingnagsf fknpivsaqv
      241 aeallaqfph aphypqangs vklaagwlid qcelkgqrig gaavhrqqal vlinedrats
      301 edvvklahyv rqrvgakfdv wlqpevrfig thgevnaees ia