MULTISPECIES: diaminopimelate epimerase [Enterobacteriaceae].

LOCUS       WP_002883394             274 aa            linear   BCT 08-FEB-2025
ACCESSION   WP_002883394
VERSION     WP_002883394.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 274)
  AUTHORS   Hor,L., Dobson,R.C., Downton,M.T., Wagner,J., Hutton,C.A. and
            Perugini,M.A.
  TITLE     Dimerization of bacterial diaminopimelate epimerase is essential
            for catalysis
  JOURNAL   J Biol Chem 288 (13), 9238-9248 (2013)
   PUBMED   23426375
REFERENCE   2  (residues 1 to 274)
  AUTHORS   Usha,V., Dover,L.G., Roper,D.L. and Besra,G.S.
  TITLE     Characterization of Mycobacterium tuberculosis diaminopimelic acid
            epimerase: paired cysteine residues are crucial for racemization
  JOURNAL   FEMS Microbiol Lett 280 (1), 57-63 (2008)
   PUBMED   18269631
REFERENCE   3  (residues 1 to 274)
  AUTHORS   Koo,C.W. and Blanchard,J.S.
  TITLE     Chemical mechanism of Haemophilus influenzae diaminopimelate
            epimerase
  JOURNAL   Biochemistry 38 (14), 4416-4422 (1999)
   PUBMED   10194362
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00652.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..274
                     /gene="dapF"
     Protein         1..274
                     /product="diaminopimelate epimerase"
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=29946
     Region          1..274
                     /region_name="DapF"
                     /note="Diaminopimelate epimerase [Amino acid transport and
                     metabolism]; COG0253"
                     /db_xref="CDD:440023"
ORIGIN      
        1 mqfskmhglg ndfmvvdavt qnvffspeli rrladrhlgv gfdqllvvep pydpdldfhy
       61 rifnadgsev sqcgngarcf arfvrlkglt nkrdirvsta ngrmvlsvte ddlvrvnmge
      121 pnfepsqvpf rankaektyi mraaeqtvlc gvvsmgnphc viqvddvdta avetlgpvme
      181 sherfperan igfmqvvgrs hirlrvyerg agetqacgsg acaavavgiq qgllaetvrv
      241 elpggrldia wkgpgqplfm tgpaahvydg fihl