MULTISPECIES: glucose-1-phosphate thymidylyltransferase RfbA

LOCUS       WP_002883307             293 aa            linear   BCT 09-DEC-2024
            [Klebsiella].
ACCESSION   WP_002883307
VERSION     WP_002883307.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 293)
  AUTHORS   Ma,Y., Mills,J.A., Belisle,J.T., Vissa,V., Howell,M., Bowlin,K.,
            Scherman,M.S. and McNeil,M.
  TITLE     Determination of the pathway for rhamnose biosynthesis in
            mycobacteria: cloning, sequencing and expression of the
            Mycobacterium tuberculosis gene encoding
            alpha-D-glucose-1-phosphate thymidylyltransferase
  JOURNAL   Microbiology (Reading) 143 (Pt 3), 937-945 (1997)
   PUBMED   9084178
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01207.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..293
                     /gene="rfbA"
     Protein         1..293
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=32666
     Region          2..287
                     /region_name="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; TIGR01207"
                     /db_xref="CDD:130274"
     Site            order(6,8..9,80,83..86,108,144,159..160,170,198)
                     /site_type="active"
                     /note="substrate binding site [active]"
                     /db_xref="CDD:133019"
     Site            order(12,15..17,20..21,25..27,29..32,35,60,112..113,
                     135..138,142..143,221..223,227..228,231,234..236,239..240)
                     /site_type="active"
                     /note="tetramer interface [active]"
                     /db_xref="CDD:133019"
ORIGIN      
        1 mkgiilaggs gtrlhpitrg vskqllpiyd kpmiyyplsv lmlagireil iittpddlrd
       61 fqrllgdgse fgialhyavq ptpdglaqaf iigeaflnge paclvlgdni ffgqsfspkl
      121 rsvaartega tifgyqvmdp erfgvvefdd nfralsleek pkqpksnwav tglyfydgkv
      181 teyakrvkps ergeleitsi nqmyledgal tvellgrgfa wldtgthdsl ieasmfvqtv
      241 ekrqgfkiac leeigwrngw ldddgvkraa krlektgygq ylldllrarp rqy