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MULTISPECIES: UDP-N-acetylglucosamine--undecaprenyl-phosphate


LOCUS       WP_002883295             367 aa            linear   BCT 23-MAY-2024
            N-acetylglucosaminephosphotransferase [Klebsiella].
ACCESSION   WP_002883295
VERSION     WP_002883295.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 367)
  AUTHORS   Amer,A.O. and Valvano,M.A.
  TITLE     Conserved amino acid residues found in a predicted cytosolic domain
            of the lipopolysaccharide biosynthetic protein WecA are implicated
            in the recognition of UDP-N-acetylglucosamine
  JOURNAL   Microbiology (Reading) 147 (Pt 11), 3015-3025 (2001)
   PUBMED   11700352
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02380.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..367
                     /gene="wecA"
     Protein         1..367
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /EC_number="2.7.8.33"
                     /GO_component="GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity,
                     for other substituted phosphate groups [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0036380 -
                     UDP-N-acetylglucosamine-undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=40699
     Region          7..349
                     /region_name="ECA_wecA"
                     /note="undecaprenyl-phosphate alpha-N-acetylglucosaminyl
                     1-phosphatetransferase; TIGR02380"
                     /db_xref="CDD:131433"
ORIGIN      
        1 mnlltaitel isiflfttlf ifvarkvakk iglvdkpnyr krhqgliplv ggisvyagic
       61 ftfaiadyyi phaslylaca gvlvlvgald drfdisvkir aviqaaiavi mmmagnlhls
      121 slgfifgswe lvlgpfgffl tlfavwaain afnmvdgidg llgglssvsf aatgiilwfd
      181 gqyslamwcf amiaailpyi llnlgalgrr ykvfmgdags tmigftiiwi llettqgkth
      241 pispvtalwi iaiplmdmva imyrrlrkgm spfspdrqhi hhlimragft srqafvlitl
      301 aaallalvgv vaeytrivpe wvmlilflva fflygycikr awkvarlvkr irrrirrhsg
      361 nnpkltk