MULTISPECIES: LysR family transcriptional regulator [Klebsiella].

LOCUS       WP_002883211             308 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002883211
VERSION     WP_002883211.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 308)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 308)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444097
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..308
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=34681
     Region          7..65
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          97..296
                     /region_name="PBP2_DntR_NahR_LinR_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulators that are involved in
                     the catabolism of dinitrotoluene, naphthalene and
                     gamma-hexachlorohexane; contains the type 2 periplasmic
                     binding fold; cd08459"
                     /db_xref="CDD:176148"
     Site            order(103,105..106,110,168,205,272)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:176148"
     Site            order(104,107..108,111..112,115..116,118..119,122..123,
                     126..130,132,194,222..226,229..230,233..234,237,251)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176148"
ORIGIN      
        1 mreeldfksl rffsalyrlg nvspaadald isqptgslll kklrdhfadp lfvrvgqrmi
       61 ptpradaiap tistllqlad ndlavkpefl pqqsqrnfti gmtdisqmtl lpllqialqq
      121 qaadgitftv qnldeqtlna lesgkcdlai gyltqlpesv yqqhlfdqsy vclaaenhpr
      181 iraqlraedw rqekhlairv egtahgdmdk lldehhmprr ialtlpsflg tgelvaesdm
      241 iavvpeqvar hitrrypcrs wplpfplaki airqvwhqrl hrdpghiwlr sliatladpa
      301 qqstsiki