MULTISPECIES: bifunctional metallophosphatase/5'-nucleotidase

LOCUS       WP_002882946             518 aa            linear   BCT 24-DEC-2024
            [Klebsiella].
ACCESSION   WP_002882946
VERSION     WP_002882946.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 518)
  AUTHORS   Matange,N., Podobnik,M. and Visweswariah,S.S.
  TITLE     Metallophosphoesterases: structural fidelity with functional
            promiscuity
  JOURNAL   Biochem J 467 (2), 201-216 (2015)
   PUBMED   25837850
REFERENCE   2  (residues 1 to 518)
  AUTHORS   Koonin,E.V.
  TITLE     Conserved sequence pattern in a wide variety of phosphoesterases
  JOURNAL   Protein Sci 3 (2), 356-358 (1994)
   PUBMED   8003970
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11432654
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..518
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=56552
     Region          20..499
                     /region_name="UshA"
                     /note="2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or
                     3'-nucleotidase, 5'-nucleotidase family [Nucleotide
                     transport and metabolism, Defense mechanisms]; COG0737"
                     /db_xref="CDD:440500"
ORIGIN      
        1 mklktmsaal lltlpfwaca kdvtiiytnd lhahvepykv pwiadgkrdi ggwanittmv
       61 kqekaknnat wffdagdyfs gpyissltkg kaiidimntm sydavtignh efdhgwdntl
      121 lqlsqatfpi vqgnifyqns dksfwdkpyt iiekdgvkig viglhgvfaf ndtvsaatrv
      181 gieardevkw lqhyidelng kvdltvalih egvparqssq ggtdvrrald kdiqtagqvk
      241 sldvlitgha hvgtpepikv gntlilstds ggidvgklvl dyqekphqft vkhfelktly
      301 adewkpdpqt kqvidgwnkq ldqlvqqvit qspveltray gissplgnla adalllaagr
      361 stqmaltnsg girneipaga vsmgavistf pfpnelvtmd ltgkqlrslm ehgaglsngv
      421 lqvsrglemm ydsskpvgqr vvlfrlngkp iddttvyhia tnsfladggd gfvaftegqa
      481 rntsggyyvs navvdyfkag qkitdeqlng qrvvdvkk