MULTISPECIES: cystathionine gamma-synthase [Klebsiella].

LOCUS       WP_002882943             386 aa            linear   BCT 13-MAY-2021
ACCESSION   WP_002882943
VERSION     WP_002882943.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005961.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..386
                     /gene="metB"
     Protein         1..386
                     /product="cystathionine gamma-synthase"
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /calculated_mol_wt=41427
     Region          1..386
                     /region_name="PRK08045"
                     /note="cystathionine gamma-synthase; Provisional"
                     /db_xref="CDD:169194"
     Site            order(29..32,34..35,46,48,74..75,77..78,101,106,109,197,
                     205,207,224,234,236..237,316)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,144,173,195,197..198,207)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,173,176,195,197..198)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            198
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 mtrkqatiav rsglnddeqy gcvvppihls stynftgfne prahdysrrg nptrdvvqra
       61 laeleggaga vltntgmsai llvttvflkp gdllvaphdc yggsyrlfds lakrgcyrvq
      121 fvdqsdeqal raalaekpkl vlvespsnpl lrvvdiakic glareagais vvdntflspa
      181 lqnplalgad lvlhsctkyl nghsdvvagv viakdpttvt elawwannig vtgsafdsyl
      241 llrglrtlsp rmevaqrnal aiveylktqp lvkklyhpsl penqgheiaa rqqkgfgaml
      301 sfeldgdeqt lrrflsglsl ftlaeslggv eslishaatm thagmapear aaagisetll
      361 ristgiedge dliadlengf raanee