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formate dehydrogenase-N subunit alpha [Klebsiella pneumoniae].


LOCUS       WP_002882823             804 aa            linear   BCT 10-JUN-2024
ACCESSION   WP_002882823
VERSION     WP_002882823.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 804)
  AUTHORS   Berg,B.L., Li,J., Heider,J. and Stewart,V.
  TITLE     Nitrate-inducible formate dehydrogenase in Escherichia coli K-12.
            I. Nucleotide sequence of the fdnGHI operon and evidence that opal
            (UGA) encodes selenocysteine
  JOURNAL   J Biol Chem 266 (33), 22380-22385 (1991)
   PUBMED   1834669
REFERENCE   2  (residues 1 to 804)
  AUTHORS   Stewart,V.
  TITLE     Nitrate respiration in relation to facultative metabolism in
            enterobacteria
  JOURNAL   Microbiol Rev 52 (2), 190-232 (1988)
   PUBMED   3045516
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01553.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..804
                     /gene="fdnG"
     Protein         1..804
                     /product="formate dehydrogenase-N subunit alpha"
                     /EC_number="1.17.5.3"
                     /GO_component="GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /GO_function="GO:0047111 - formate dehydrogenase
                     (cytochrome-c-553) activity [Evidence IEA]"
                     /GO_process="GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=89232
     Region          <1..803
                     /region_name="Molybdopterin-Binding"
                     /note="Molybdopterin-Binding (MopB) domain of the MopB
                     superfamily of proteins, a large, diverse, heterogeneous
                     superfamily of enzymes that, in general, bind
                     molybdopterin as a cofactor. The MopB domain is found in a
                     wide variety of molybdenum- and...; cl09928"
                     /db_xref="CDD:447860"
     Site            order(17..18,20,23..24,46..48,68,197,344..346,370..372,
                     375,404..405,410)
                     /site_type="other"
                     /note="molybdopterin cofactor binding site"
                     /db_xref="CDD:238218"
ORIGIN      
        1 mtnhwvdikn anlvvvmggn aaeahpvgfr wameakihng aklividprf trtasvadfy
       61 tpirsgtdit flsgvilyll nnekfnreyt eaytnasliv redysfddgl fsgydaekrq
      121 ydktswnyel dengfakrdt tlqhprcvwn llkqhvsryt pdvvenicgt pkadflkvce
      181 yiaetsapdk tasflyalgw tqhsigaqni rtmamiqlll gnmgmagggv nalrghsniq
      241 gltdlgllst slpgymslpn ekqadlqtyl tantpkpllk dqvnywgnyp kffvsmmkaf
      301 fgdkataens wgydwlpkwd ksydvlqyfe mmnqgkvngy icqgfnpvas fpnknkvvas
      361 lsklkflvti dplntetstf wqnhgesndv dpakiqtevf rlpstcfaee ngsivnsgrw
      421 lqwhwkgada pgiavtdgei lagiftrlrk myaeeggpap epvlnmtwny stphepasee
      481 vamesngkal aditdpatga vivkkgqqls sfaqlrddgt tssgcwifag swtpegnqma
      541 rrdnadpsgl gntlgwawaw plnrrilynr asadpqgkpw dpkrqllkwd gakwggvdip
      601 dysaaapgsd vgpfimqpeg mgrlfaidkm aegpfpehye pfetplgtnp lhpnvvsnpa
      661 arvfkgdleq mgkaekfpyv gttyrltehf hywtkhalln aiaqpeqfve igeklanklg
      721 ighgdtvkvs snrgyikaka vvtkrirtlk vdgkdidtig ipihwgyegv akkgfiantl
      781 tpfvgdantq tpefkaflvn vekv