methionine synthase [Grimontia indica].

LOCUS       WP_002541277            1224 aa            linear   BCT 27-MAR-2023
ACCESSION   WP_002541277
VERSION     WP_002541277.1
KEYWORDS    RefSeq.
SOURCE      Grimontia indica
  ORGANISM  Grimontia indica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Grimontia.
REFERENCE   1  (residues 1 to 1224)
  AUTHORS   Dixon,M.M., Huang,S., Matthews,R.G. and Ludwig,M.
  TITLE     The structure of the C-terminal domain of methionine synthase:
            presenting S-adenosylmethionine for reductive methylation of B12
  JOURNAL   Structure 4 (11), 1263-1275 (1996)
   PUBMED   8939751
REFERENCE   2  (residues 1 to 1224)
  AUTHORS   Drummond,J.T., Loo,R.R. and Matthews,R.G.
  TITLE     Electrospray mass spectrometric analysis of the domains of a large
            enzyme: observation of the occupied cobalamin-binding domain and
            redefinition of the carboxyl terminus of methionine synthase
  JOURNAL   Biochemistry 32 (36), 9282-9289 (1993)
   PUBMED   8369296
REFERENCE   3  (residues 1 to 1224)
  AUTHORS   Luschinsky,C.L., Drummond,J.T., Matthews,R.G. and Ludwig,M.L.
  TITLE     Crystallization and preliminary X-ray diffraction studies of the
            cobalamin-binding domain of methionine synthase from Escherichia
            coli
  JOURNAL   J Mol Biol 225 (2), 557-560 (1992)
   PUBMED   1593636
REFERENCE   4  (residues 1 to 1224)
  AUTHORS   Banerjee,R.V., Johnston,N.L., Sobeski,J.K., Datta,P. and
            Matthews,R.G.
  TITLE     Cloning and sequence analysis of the Escherichia coli metH gene
            encoding cobalamin-dependent methionine synthase and isolation of a
            tryptic fragment containing the cobalamin-binding domain
  JOURNAL   J Biol Chem 264 (23), 13888-13895 (1989)
   PUBMED   2668277
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007024.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09490
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1224
                     /organism="Grimontia indica"
                     /db_xref="taxon:1056512"
     gene            1..1224
                     /gene="metH"
     Protein         1..1224
                     /product="methionine synthase"
                     /EC_number="2.1.1.13"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008705 - methionine synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=135930
     Region          1..1223
                     /region_name="metH"
                     /note="B12-dependent methionine synthase; Provisional;
                     PRK09490"
                     /db_xref="CDD:236539"
ORIGIN      
        1 mssketlekl laeriliidg gmgtmiqgyk leeddyrger fadwhcdlkg nndllvltqp
       61 qmikdihaey leagadilet ntfnattiam adyemeslse einfaaakla revadewtak
      121 npdkprfvag vlgptnrtcs ispdvndpgy rnvsfdelvt aysestrali nggadlilie
      181 tifdtlnaka cafavetvfe emgtqlpvmi sgtitdasgr tlsgqtteaf ynslrhvkpi
      241 sfglncalgp delrpyveel srisetfvsa hpnaglpnaf geydlspedm aahvkewaes
      301 gflnmiggcc gttpehirhm yeatktvkpr alpdlqvacr lsglepltie ketlfinvge
      361 rtnvtgsarf krlikeeqyd ealevarqqv engaqiidin mdegmldaea cmvrflnlca
      421 sepeiskvpi mvdsskwevi eaglkciqgk givnsislke gkekfveqak lirrygaavi
      481 vmafdevgqa etrerkleic tnayrilvde vgfppediif dpnifavatg ieehnnyavd
      541 fidavadikr dlpyamisgg vsnvsfsfrg nnyvreaiha vflyhcfkng mdmgivnagq
      601 leiydnvpek lreavedvvl nrrddsterl ldiaaeyank gvgkeedasa lewrtwavek
      661 rlehalvkgi tefivedtee arvnaskple viegplmdgm nvvgdlfgeg kmflpqvvks
      721 arvmkqavah lepfinaekq agstngkill atvkgdvhdi gknivgvvlq cnnydiidlg
      781 vmvpcekilk vakeenvdii glsglitpsl demvhvakem erlgfdlpll iggattskah
      841 tavkieqnyn qpvvyvnnas ravgvcssll seklkpafve klqadyevvr eqharkrprt
      901 kpvtlekare nkvaidwesy tppapakpgv hvfedfdvat lrnyidwtpf fmtwslvgky
      961 ptileheevg eeakrlfkda ndlldrvere glmkasgmca lfpaasvgdd ievytdesrt
     1021 evakvlhnlr qqtekpkgfn yclsdyiapk esgkkdwiga favtggiger eladeykaqg
     1081 ddynaimiqa vadrlaeafa eylhahvrke iwgyaadenl snddlireky qgirpapgyp
     1141 acpehtekgt lwellnveet igmslttsya mwpgasvsgw yfshpdsryf avaqiqedqr
     1201 dsyadrkgwd lieaekwlgp nlng