MDR family oxidoreductase [Vibrio cholerae].

LOCUS       WP_001897942             326 aa            linear   BCT 06-NOV-2024
ACCESSION   WP_001897942
VERSION     WP_001897942.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 326)
  AUTHORS   Persson,B., Hedlund,J. and Jornvall,H.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the MDR superfamily
  JOURNAL   Cell Mol Life Sci 65 (24), 3879-3894 (2008)
   PUBMED   19011751
REFERENCE   2  (residues 1 to 326)
  AUTHORS   Auld,D.S. and Bergman,T.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : The role of zinc for alcohol dehydrogenase structure and
            function
  JOURNAL   Cell Mol Life Sci 65 (24), 3961-3970 (2008)
   PUBMED   19011745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10169682
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Vibrio cholerae"
                     /db_xref="taxon:666"
     Protein         1..326
                     /product="MDR family oxidoreductase"
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /calculated_mol_wt=34360
     Region          2..324
                     /region_name="MDR_yhdh"
                     /note="Yhdh putative quinone oxidoreductases; cd08288"
                     /db_xref="CDD:176248"
     Site            order(41..42,127..128,131,155,157..160,179..181,200,
                     221..222,243..247,268..271,313,316,318)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:176248"
     Site            order(209,236,242..245,251,253..256,258..260,262..269,
                     272..273)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:176248"
ORIGIN      
        1 mfnallltqq dktthatvtq inddqlpagn vtvavnyssl nykdglaitg kgkiirefpm
       61 vpgidfagtv lesadaryqv gdavvltgwg vgenhwggma qkarlnadwl vklpqgltsq
      121 qammigtagf tamlcvqali dggikpqdge ilvtgasggv gsvavtllaq lgykvvavtg
      181 rvaqngpfle qlgasrvidr qeiseasrpl ekqlwvgavd tvgskvlakv laqmhyngvv
      241 aacglaggfd lpttvmpfil rnvrlqgvds vscpvekrla awkklaellp asyyaqache
      301 islsqvpeya eaitngqvtg rvvvkl