DsbC family protein [Vibrio cholerae].

LOCUS       WP_001896353             230 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_001896353
VERSION     WP_001896353.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Qi,Y. and Grishin,N.V.
  TITLE     Structural classification of thioredoxin-like fold proteins
  JOURNAL   Proteins 58 (2), 376-388 (2005)
   PUBMED   15558583
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Collet,J.F. and Bardwell,J.C.
  TITLE     Oxidative protein folding in bacteria
  JOURNAL   Mol Microbiol 44 (1), 1-8 (2002)
   PUBMED   11967064
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Shao,F., Bader,M.W., Jakob,U. and Bardwell,J.C.
  TITLE     DsbG, a protein disulfide isomerase with chaperone activity
  JOURNAL   J Biol Chem 275 (18), 13349-13352 (2000)
   PUBMED   10788443
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Chen,J., Song,J.L., Zhang,S., Wang,Y., Cui,D.F. and Wang,C.C.
  TITLE     Chaperone activity of DsbC
  JOURNAL   J Biol Chem 274 (28), 19601-19605 (1999)
   PUBMED   10391895
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Aslund,F. and Beckwith,J.
  TITLE     The thioredoxin superfamily: redundancy, specificity, and gray-area
            genomics
  JOURNAL   J Bacteriol 181 (5), 1375-1379 (1999)
   PUBMED   10049365
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Chivers,P.T., Prehoda,K.E. and Raines,R.T.
  TITLE     The CXXC motif: a rheostat in the active site
  JOURNAL   Biochemistry 36 (14), 4061-4066 (1997)
   PUBMED   9099998
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10122483
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Vibrio cholerae"
                     /db_xref="taxon:666"
     Protein         1..230
                     /product="DsbC family protein"
                     /GO_function="GO:0003756 - protein disulfide isomerase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=25007
     Region          30..227
                     /region_name="DsbA_DsbC_DsbG"
                     /note="DsbA family, DsbC and DsbG subfamily; V-shaped
                     homodimeric proteins containing a redox active CXXC motif
                     imbedded in a TRX fold. They function as protein disulfide
                     isomerases and chaperones in the bacterial periplasm to
                     correct non-native disulfide bonds...; cd03020"
                     /db_xref="CDD:239318"
     Site            order(30..37,40..67)
                     /site_type="other"
                     /note="dimerization domain [polypeptide binding]"
                     /db_xref="CDD:239318"
     Site            60..67
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:239318"
     Site            order(120,123)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239318"
ORIGIN      
        1 mrklspiila lalsplvqae pvsevspvgk idgmvslpvt gmkavesngr ivfmsdsgrf
       61 vidgtlydaw skkpltslee ireagntldl srlglkmndl npltlgegkk kvvvfvdprc
      121 phchellkqa lpltkeytfq ilpvpvlgpd serqvrqlgc ardkkaatda llngrignle
      181 qddacnlepm qrtlvtaqil giqgvpfiva ndgrisrgrp ydlsawlegr