MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_001737995             446 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_001737995
VERSION     WP_001737995.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 446)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 446)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 446)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022776
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..446
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=49164
     Region          20..418
                     /region_name="MFS_SV2_like"
                     /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and
                     related small molecule transporters of the Major
                     Facilitator Superfamily; cd17316"
                     /db_xref="CDD:340874"
     Site            order(30..31,34..35,38,70,120..121,123..125,128,148,
                     151..152,155,252,255..256,259..261,264,292,296,347..348,
                     352,356,372,375..376,379..380,383)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340874"
ORIGIN      
        1 mqqprnfddl kfssihrrim lwgsggpfld gyvlviigva leqltpllhl daewigalga
       61 atlaglfigt slfgyicdkv grrkmflldi iaigvisvat mfvstplell vmrvligivi
      121 gadypiatsm itefsntrqr afsigfiaam wyvgatcanl vgywlydmeg gwrwmlgsaf
      181 ipcliiligr fdlpesprwl lrkgrvkece qmmiklfgep vcfddelpqe trflqlfnrr
      241 hfpfvlfvaa iwtcqvipmf aiytfgpqiv gllgweqgrn aalgnvvisl ffmlgcipam
      301 fwlnsigrrp lligsfammt ialallglvs nlgiilvvva favyaffsgg pgilqwlypn
      361 elfptdiras avgvimslsr igtivstwal pifitrygin nvmligalis lvglgvsvmf
      421 apetrgltlt qtgnmtlrgt psdnpr