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EAL domain-containing protein [Salmonella enterica].


LOCUS       WP_001687156             567 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_001687156
VERSION     WP_001687156.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 567)
  AUTHORS   Simm,R., Morr,M., Kader,A., Nimtz,M. and Romling,U.
  TITLE     GGDEF and EAL domains inversely regulate cyclic di-GMP levels and
            transition from sessility to motility
  JOURNAL   Mol Microbiol 53 (4), 1123-1134 (2004)
   PUBMED   15306016
REFERENCE   2  (residues 1 to 567)
  AUTHORS   D'Argenio,D.A. and Miller,S.I.
  TITLE     Cyclic di-GMP as a bacterial second messenger
  JOURNAL   Microbiology (Reading) 150 (Pt 8), 2497-2502 (2004)
   PUBMED   15289546
REFERENCE   3  (residues 1 to 567)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11471819
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     Protein         1..567
                     /product="EAL domain-containing protein"
                     /EC_number="3.1.4.52"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=63449
     Region          44..557
                     /region_name="YjcC"
                     /note="Redox-sensing c-di-GMP phosphodiesterase, contains
                     CSS-motif and EAL domains [Signal transduction
                     mechanisms]; COG4943"
                     /db_xref="CDD:443970"
ORIGIN      
        1 mgeifissss tprfpttlav srlafvanay waarmqtaqr iinhyrrnrf ivcticalvt
       61 liltlsirfi sernlnhhrt vafanhavda ldnvlhpllv grnillplle lpcatahlpl
      121 rkqaarlqti rsiglvkegi lycssifgar ntpirqlqpd lpavgdllll stdqsllkgs
      181 piliqwypas adgqdgvmei vnidllttml lepqqpqits asltvgkrhl lygrgvvdtl
      241 pelkkdeery qlssrhfpft isvsgpsagv lafkhlptql plavllslli gyiawlatas
      301 rmsfsweinl alaerefelf cqpllnartq qctgveillr wnnprqgwis pdvfipiaee
      361 hnliapltry viaetirqrh yfpinhqfhi ginvaashfr hgvllkdlnq ywfsaepvqq
      421 lvlelterda lldvdyrlmr elhrkgvkla iddfgtgnss lswleklrpd ilkidksfta
      481 aigtdavnst vtdiiialgq rlnielvaeg venqtqaqhl rqhgvqmlqg ylyakpmpis
      541 efpqwlagsa ppparhngqi msamphl