peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase

LOCUS       WP_001663100             858 aa            linear   BCT 01-JUL-2024
            MrcA [Salmonella enterica].
ACCESSION   WP_001663100
VERSION     WP_001663100.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 858)
  AUTHORS   Egan,A.J., Biboy,J., van't Veer,I., Breukink,E. and Vollmer,W.
  TITLE     Activities and regulation of peptidoglycan synthases
  JOURNAL   Philos Trans R Soc Lond B Biol Sci 370 (1679) (2015)
   PUBMED   26370943
REFERENCE   2  (residues 1 to 858)
  AUTHORS   Born,P., Breukink,E. and Vollmer,W.
  TITLE     In vitro synthesis of cross-linked murein and its attachment to
            sacculi by PBP1A from Escherichia coli
  JOURNAL   J Biol Chem 281 (37), 26985-26993 (2006)
   PUBMED   16840781
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008643.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11636
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     gene            1..858
                     /gene="mrcA"
     Protein         1..858
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /EC_number="2.4.99.28"
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /calculated_mol_wt=94289
     Region          9..858
                     /region_name="mrcA"
                     /note="penicillin-binding protein 1a; Provisional;
                     PRK11636"
                     /db_xref="CDD:183248"
ORIGIN      
        1 mtlngkspvk fvkyllilav ccillgagsi yglyryiepq lpdvatlkdv rlqipmqvys
       61 adgeliaqyg ekrripvtld qippeminaf iatedsrfye hhgidpvgif raasvalfsg
      121 hasqgastit qqlarnffls pertlmrkik eaflairieq llnkneilel ylnkiylgyr
      181 aygvgaaaqv yfgktvdqls lsemaviagl pkapstfnpl ysmdraiarr nvvlsrmlse
      241 gyitqaqydq arsepidany hapeiafsap ylsemvrqem ynrygesaye dgyriyttit
      301 rkvqqaaqqa vrnnvldydm rhgyrgpanv lwkvgetawd skkitdtlka lptygpllpa
      361 vvtsanpqea taaladgtsv slhmegmrwa rpyrsdtqqg ptprkvtdvv qtgqqiwvrq
      421 vdndwwlaqv pevnsalvsl npqtgavlal vggfdfnqsk fnratqalrq vgsnikpfly
      481 taamdkgltl asmlndvpis rwdagagsdw rpknsppqya gpirlrqglg qsknvvmvra
      541 mramgvdyaa eylqrfgfpa qnivhtesla lgsasftpmq vargyavman ggflidpyfi
      601 skiendqggv ifeakpkiac pecdipviyg ntqksdvlen tnveevavsq eqqnsavpmp
      661 eleqanqalv aqngtqeyap hvintplafl iksalntnif gepgwmgtgw raardlkrrd
      721 iggktgttns skdawfsgyg pgvvtsvwig fddhrrdlgr ttasgaikdq isgyeggaks
      781 aqpawdaymk avlegvpeqp ltpppgivtv nidrstgqla sggnsreeyf iegtqptqqa
      841 vhevgttiid ngethelf