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LOCUS WP_001576584 343 aa linear BCT 20-MAR-2023 ACCESSION WP_001576584 VERSION WP_001576584.1 KEYWORDS RefSeq. SOURCE Salmonella enterica ORGANISM Salmonella enterica Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. REFERENCE 1 (residues 1 to 343) AUTHORS Bateman,A. TITLE The SIS domain: a phosphosugar-binding domain JOURNAL Trends Biochem Sci 24 (3), 94-95 (1999) PUBMED 10203754 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11454870 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..343 /organism="Salmonella enterica" /db_xref="taxon:28901" Protein 1..343 /product="SIS domain-containing protein" /EC_number="3.5.-.-" /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /GO_function="GO:0097367 - carbohydrate derivative binding [Evidence IEA]" /GO_process="GO:0005975 - carbohydrate metabolic process [Evidence IEA]" /calculated_mol_wt=39089 Region 25..340 /region_name="AgaS" /note="Fructoselysine-6-P-deglycase FrlB or related protein, duplicated sugar isomerase (SIS) domain [Cell wall/membrane/envelope biogenesis]; COG2222" /db_xref="CDD:441824" Region 44..162 /region_name="SIS_1" /note="A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; cd05710" /db_xref="CDD:240214" Site order(53,98) /site_type="active" /note="putative active site [active]" /db_xref="CDD:240214" ORIGIN 1 mnnqeknmlg fnqdeyltsa reiiaarqka eqvadeiyqa gfsslffasv ggslapmmai 61 nefakelttl pvyveqaael ihkgnkrlnk dsvvitlsks gdtkesvaia ewckaqgirv 121 vaitknadsp laqaatwhip mrhkngveye ymllywlffr vlsrnnefas ydrfasqlei 181 lpanllkakq kfdpqadaia sryhnsdymm wvggaemwge vylfsmcile emqwkrtrpv 241 ssaeffhgal ellekdvpli lvkgegkcra lderverfas kitdnlvvid pkayaldgid 301 defrwimapc vvstllvdrl aahfekytgh sldirryyrq fdy