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SIS domain-containing protein [Salmonella enterica].


LOCUS       WP_001576584             343 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_001576584
VERSION     WP_001576584.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 343)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454870
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     Protein         1..343
                     /product="SIS domain-containing protein"
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=39089
     Region          25..340
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
     Region          44..162
                     /region_name="SIS_1"
                     /note="A subgroup of the SIS domain. SIS (Sugar ISomerase)
                     domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. SIS domains are also found
                     in proteins that regulate the expression of genes involved
                     in synthesis of phosphosugars; cd05710"
                     /db_xref="CDD:240214"
     Site            order(53,98)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:240214"
ORIGIN      
        1 mnnqeknmlg fnqdeyltsa reiiaarqka eqvadeiyqa gfsslffasv ggslapmmai
       61 nefakelttl pvyveqaael ihkgnkrlnk dsvvitlsks gdtkesvaia ewckaqgirv
      121 vaitknadsp laqaatwhip mrhkngveye ymllywlffr vlsrnnefas ydrfasqlei
      181 lpanllkakq kfdpqadaia sryhnsdymm wvggaemwge vylfsmcile emqwkrtrpv
      241 ssaeffhgal ellekdvpli lvkgegkcra lderverfas kitdnlvvid pkayaldgid
      301 defrwimapc vvstllvdrl aahfekytgh sldirryyrq fdy