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diaminopimelate epimerase [Salmonella enterica].


LOCUS       WP_001576444             275 aa            linear   BCT 19-MAY-2021
ACCESSION   WP_001576444
VERSION     WP_001576444.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 275)
  AUTHORS   Hor,L., Dobson,R.C., Downton,M.T., Wagner,J., Hutton,C.A. and
            Perugini,M.A.
  TITLE     Dimerization of bacterial diaminopimelate epimerase is essential
            for catalysis
  JOURNAL   J Biol Chem 288 (13), 9238-9248 (2013)
   PUBMED   23426375
REFERENCE   2  (residues 1 to 275)
  AUTHORS   Usha,V., Dover,L.G., Roper,D.L. and Besra,G.S.
  TITLE     Characterization of Mycobacterium tuberculosis diaminopimelic acid
            epimerase: paired cysteine residues are crucial for racemization
  JOURNAL   FEMS Microbiol Lett 280 (1), 57-63 (2008)
   PUBMED   18269631
REFERENCE   3  (residues 1 to 275)
  AUTHORS   Koo,C.W. and Blanchard,J.S.
  TITLE     Chemical mechanism of Haemophilus influenzae diaminopimelate
            epimerase
  JOURNAL   Biochemistry 38 (14), 4416-4422 (1999)
   PUBMED   10194362
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00652.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     gene            1..275
                     /gene="dapF"
     Protein         1..275
                     /product="diaminopimelate epimerase"
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=30337
     Region          1..275
                     /region_name="DapF"
                     /note="Diaminopimelate epimerase [Amino acid transport and
                     metabolism]; COG0253"
                     /db_xref="CDD:440023"
ORIGIN      
        1 mmqfskmhgl gndfmvvdav tqnvffspel irrlsdrhlg vgfdqllvve ppydpeldfh
       61 yrifnadgse vsqcgngarc farfvrlkgl tnkrdirvst angrmvlsvt edelvrvnmg
      121 epnfepaqvp frankaekty imraaeqtil cgvvsmgnph cviqvdnvdt aavetlgpvl
      181 esherfpera nigfmqvvrr ehirlrvyer gagetracgs gacaavavgi qqgllaeevr
      241 velpggrldi awkgpghply mtgpaahiyd gfihl